A systematic review of clinical pharmacist interventions in paediatric hospital patients

Drovandi, Aaron; Robertson, Kelvin; Tucker, Matthew D.; Robinson, Niechole; Perks, Stephen; Kairuz, Therése

doi:10.1007/s00431-018-3187-x

Cited by 56 publications

(52 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These factors seem to have contributed towards failures observed during the use of these items 23. Other studies have also confirmed that this class of medications is commonly associated with medication errors (dosage errors) 25,26. Therefore, it is of great importance that the pharmacist monitors the use of these drugs, be available to solve doubts at the prescription process and participate in the elaboration of antimicrobial protocols.…”

Section: Discussionmentioning

confidence: 96%

Medication follow-up in newborns with extremely low birth-weight

Loureiro

Fonteles

Mascarenhas

et al. 2019

Pharm Pract (Granada)

View full text Add to dashboard Cite

Objective:The medication follow-up in infants with extremely low birth-weight in a neonatal intensive care unit is described, identifying drug-related problems (DRP), drug-related negative outcomes, and the relationship between the occurrence of DRP and birth-weight of newborns and their impact on pharmacotherapy and length of hospital stay.Methods:A descriptive and exploratory study was performed in which medication follow-up of a population of infants with extremely low birth-weight admitted to the neonatal intensive care unit of a government-run maternity hospital was carried out by clinical pharmacists. Monitoring comprised assessment of patients’ pharmacotherapy needs through visits to the neonatal unit, evaluation of prescriptions and information on medical records, identification of issues associated with pharmacotherapy and follow-up of the newborns’ clinical evolution to determine whether desired results were achieved.Results:The subjects were 33 infants characterized by extremely low weight at birth. Analysis of patients’ pharmacotherapy showed that 39.4% (n=13) of the neonates presented some type of DRP, totaling 37 DRPs and a mean of 2.8 problems/patient. Fourteen drugs were identified with the occurrence of DRP. Vancomycin and cefepime were the most prevalent, with 18.9% (n=7). Occurrence of DRPs and several clinical characteristics of newborns and their pharmacotherapy were compared. The most prevalent drug-related negative outcomes identified were “untreated health problem” (40%, n=10) and “quantitative ineffectiveness” (32%, n=8). Pharmaceutical interventions were performed for all problems associated with pharmacotherapy, with a prevalence of “treatment day count correction” and “dose correction”, both with 21.6% (n=8), and “correction of dosage” (16.2%, n=6).Conclusion:The research evidenced the role of the clinical pharmacist in the solution and prevention of drug-related problems, contributing with the multidisciplinary team to obtain a safe and effective pharmacotherapy. Further, current study confirmed that there is an association between the characteristics of the newborns under analysis (eg. birth-weight, pharmacotherapy) and the occurrence of drug-related problems.

show abstract

Section: Discussionmentioning

confidence: 96%

Medication follow-up in newborns with extremely low birth-weight

Loureiro

Fonteles

Mascarenhas

et al. 2019

Pharm Pract (Granada)

View full text Add to dashboard Cite

show abstract

“…In a previous systematic review, which investigated the benefits provided by the clinical pharmacist in pediatric hospitals, the pharmaceutical intervention resulted in a better understanding of the medication, greater adherence to treatment, greater patient satisfaction, and better control of chronic medical conditions. 36 In a meta-analysis conducted with 42 studies, the intervention of the clinical pharmacist had a significant effect on lowering blood pressure and reducing hospitalization days. 37 In general, the economic evaluations included in this review showed variable methodological quality.…”

Section: Reporting Quality Of the Studiesmentioning

confidence: 99%

Economic impact of pharmaceutical interventions on healthcare services from Brazil: a systematic review

Tiguman¹,

Junior²

2020

Rev Bras Farm Hosp Serv Saude

View full text Add to dashboard Cite

Objective: The aim of this research was to systematically review the studies that investigated the economic impact of the pharmaceutical intervention in Brazilian healthcare services. Methods: A systematic search was conducted in the MEDLINE, EMBASE, and LILACS databases to select the economic evaluations published until November 2019. Two independent authors selected the studies, extracted the data, and assessed the methodological quality using the 19-items Consensus on Health Economic Criteria (CHEC-list) instrument and the reporting quality using the 24-items Consolidated Standards of Economic Health Assessment (CHEERS) checklist. Results: Out of the 290 identified articles, 10 met the eligibility criteria. Most studies were conducted in the southeastern region of Brazil (n=7) and significantly differed in design, economic outcome measure, and type of intervention. The majority (n=8) reported that pharmaceutical practice resulted in reduction of costs and clinical benefits to patients. In general, the methodological and the reporting qualities of the studies were low/moderate with an average score at CHEC-list of 10.3 (range: 3-16 points) and at CHEERS of 15.8 (range: 11-21 points). Conclusions: The Brazilian studies indicate that the pharmacist intervention can lead to economic and clinical benefits for healthcare services. The methodological and the reporting qualities of the studies were limiting factors.

show abstract

“…Według przeglądu systematycznego piśmiennictwa przeprowadzonego przez Drovandi'ego i wsp. [10] identyfikacja błędów lekowych i rozpoczęcie interwencji należą do najczęstszych rezultatów wpływających na efekt leczenia, wynikających z pracy farmaceuty klinicznego. Zidentyfikowane błędy lekowe w grupie pacjentów pediatrycznych związane były przede wszystkim z lekami stosowanymi w antybiotykoterapii, chorobach przewodu pokarmowego i chorobach metabolicznych [11][12][13][14][15][16].…”

Section: Zapobieganie Występowaniu Błędów Lekowychunclassified

Identification of the area of service provided by clinical pharmacist in the pediatric patient care

Nowak¹,

Owczarek²,

Karolewicz³

et al. 2019

Farm Pol.

View full text Add to dashboard Cite

Identification of the area of service provided by clinical pharmacist in the pediatric patient care • The interdisciplinary cooperation between medical professions in patient care was indicated as necessary in the joint document of the The International Pharmaceutical Federation and the World Medical Assembly "The relationship between physicians and pharmacists in medical therapy". The available literature emphasizes the role of the clinical pharmacist in clinical departments, such as pediatric cardiac intensive care units, or pediatric nephrology and pediatric oncology units. This work summarizes the literature related to the most important opportunities and benefits of clinical involvement of a pharmacist in the care of a pediatric patient. The law regulations in Poland to the area of pharmacists' activity discussed in the article require supplementing and specifying the most important legal acts related to pharmaceutical law and healthcare legal services. The changes should lead to the clarification of new obligations and support shaping the new professional status of clinical pharmacists employed in hospitals to provide care in the group of pediatric patients.

show abstract

A systematic review of clinical pharmacist interventions in paediatric hospital patients

Cited by 56 publications

References 35 publications

Medication follow-up in newborns with extremely low birth-weight

Medication follow-up in newborns with extremely low birth-weight

Economic impact of pharmaceutical interventions on healthcare services from Brazil: a systematic review

Identification of the area of service provided by clinical pharmacist in the pediatric patient care

Contact Info

Product

Resources

About