A systematic review of the anti‐obesity and weight lowering effect of ginger (Zingiber officinale Roscoe) and its mechanisms of action

Abstract

Recently, the beneficial effects of ginger on obesity is taken into consideration. Albeit, it seems that the anti-obesity effect of ginger and its mechanism of action has not yet been reviewed. Therefore, the aim of this study was to systematically review the effect of Zingiber officinale Roscoe on obesity management. Databases including PubMed, Scopus, Google scholar, and Science Direct were searched from 1995 until May 2017 using the definitive keywords. Searching was limited to articles with English language. All of the relevant human and animal studies and also in vitro studies were included. Review articles, abstract in congress, and also other varieties of ginger were excluded. Eligibility of included articles were evaluated by 3 reviewers, which also extracted data. Articles were critically assessed individually for possible risk of bias. Twenty-seven articles (6 in vitro, 17 animal, and 4 human studies) were reviewed. Most of the experimental studies supported the weight lowering effect of ginger extract or powder in obese animal models, whereas the results of the available limited clinical studies showed no changes or slight changes of anthropometric measurements and body composition in subjects with obesity. Ginger could modulate obesity through various potential mechanisms including increasing thermogenesis, increasing lipolysis, suppression of lipogenesis, inhibition of intestinal fat absorption, and controlling appetite. This review article provides some convincing evidence to support the efficacy of ginger in obesity management and demonstrates the importance of future clinical trials.

Zingiber officinale Rosc. essential oil, a review on its composition and bioactivity

“…Ginger rhizomes are containing fatty oils (3-6%), proteins (9%), carbohydrates (60-70%), crude fiber (3-8%), ash (8%), water (9-12%), and volatile oil (2-3%). Nowadays, ginger hydro-ethanol extracts are extensively used as analgesic, anti-inflammatory, anticancer, anti-diabetic, hepatoprotective, nephron-protective, and antioxidant agents [5], which has been the subject of many review articles [6][7][8]. The aim of this review article was to investigate the chemical composition of ginger essential oil and its pharmacological effects according to published literatures up to December 2017.…”

Comprehensive Study of Scientific Evidence and Potential Risk of Herbal Medicine Use for Body Weight Reduction in North West Saudi Arabia

“…Some of the remedies used in Tabuk area were previously approved for their efficacy in reducing weight such as ginger [10], cinnamon [11], green tea [12], coffee beans [13], chili [14], hibiscus [15], curcumin [16], kidney beans [17], and cumin [18]. We want to add that most of the studies on weight reduction remedies were performed only on animals, and very little studies were performed on humans.…”

Does ginger supplementation lower blood pressure? A systematic review and meta‐analysis of clinical trials

“…Ginger with the scientific name of Zingiber officinale is one of the most widely used spices and medicinal plants around the world, especially in Asian countries (Ebrahimzadeh Attari et al, 2018;Pourmasoumi et al, 2018). Traditionally, this spice was administered to treat nervous diseases, gastrointestinal problems, cataract, rheumatism, diabetes, and nausea caused by pregnancy and chemotherapy (Chen, May, Zhou, Zhang, & Xue, 2016;Langner, Greifenberg, & Gruenwald, 1998;White, 2007).…”