A systematic review on the association of serum selenium and metabolic syndrome

Tajaddini, Mohammad Hasan; Keikha, Mojtaba; Razzazzadeh, Ali; Kelishadi, Roya

doi:10.4103/1735-1995.168403

Cited by 18 publications

(7 citation statements)

References 49 publications

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“…Moreover, selenium blood levels are related to a decrease in ROS production; consequently, selenium seems to have a protective role against oxidative stress-associated disorders, including cardiovascular disease [21,22]. In the present systematic review, only one study with selenium was available [44].…”

Section: Discussionmentioning

confidence: 97%

“…Research has associated chromium, vanadium, and zinc with insulin action and glucose metabolism [17][18][19][20]; chromium, silicon, zinc, and copper with angiogenesis and vascular biology [13]; and zinc and selenium with oxidative stress and cardiovascular diseases [20][21][22]. Trace elements, such as copper, zinc, and iron, are involved in cytokine production, inflammation, and immune defense [15,23], and copper acts as enzyme cofactors or regulators of transcription factors [24].…”

Section: Introductionmentioning

confidence: 98%

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Blood Trace Element Concentrations in Polycystic Ovary Syndrome: Systematic Review and Meta-analysis

Spritzer

Lecke

Fabris

et al. 2016

Biol Trace Elem Res

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Polycystic ovary syndrome (PCOS) is a prevalent condition in women of reproductive age. PCOS is characterized by androgen excess and chronic anovulation and associated with low-grade inflammation and metabolic comorbidities. Some trace elements have been linked to pathophysiological mechanisms of oxidative stress and inflammation in different disorders. Therefore, we conducted a systematic review and meta-analysis of the available evidence regarding trace element concentrations in PCOS. We reviewed MEDLINE and EMBASE in search of case-control, cross-sectional, and cohort studies published until September 2015. Of 183 studies identified, six were selected for systematic review. All used the Rotterdam criteria for the diagnosis of PCOS. Two studies evaluating chromium and one assessing cobalt levels did not observe differences between PCOS and controls. Another study recorded similar nickel and vanadium levels between the groups, but lower selenium concentrations in women with PCOS compared to controls. Four studies were included in the random effects model meta-analysis, for a total of 264 PCOS and 151 control women. Copper levels were found to be higher in women with PCOS than in controls [mean difference 0.12 ppm (95 % CI 0.07; 0.17 ppm); I 2 = 0 %]. Manganese [mean difference 0.04 ppm (95 % CI −0.05; 0.13 ppm); I 2 = 94.4 %] and zinc concentrations [mean difference 0.02 ppm (95 % CI −0.12; 0.16 ppm); I 2 = 92.4 %] were similar between the groups. The present results suggest a relationship between increased copper concentration and PCOS. This systematic review and meta-analysis is registered in PROSPERO under number CRD42016034036.

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Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 98%

Blood Trace Element Concentrations in Polycystic Ovary Syndrome: Systematic Review and Meta-analysis

Spritzer

Lecke

Fabris

et al. 2016

Biol Trace Elem Res

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“…Although obesity is commonly associated with many cardiometabolic diseases like hypertension and diabetes (Odu-wole et al, 2012), research has reported localized adipose tissue or its distribution, particularly an android fat pattern with excessive fat around the abdomen to be more closely associated with these diseases than obesity itself (Ben Mohammed et al, 2011;Buchan et al, 2013). These findings have renewed the scientific community's interest in studying body fat distribution and its relative effect on health, especially among the youth (Lee & Arslanian, 2007;Kelishadi et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…The waist circumference (WC), a proxy measure of abdominal fat distribution (Maffies, 2000) is a component of metabolic syndrome, the coexistence of many cardiovascular disease risk factors in an individual which is linked to type 2 diabetes mellitus, coronary heart disease, and some types of cancer (Kelishadi et al, 2015). Although abdominal fat is considered a chronic disease risk, visceral adipose tissue (VAT) (intrabdominal fat depot) is strongly associated with metabolic abnormalities than subcutaneous adipose tissue (SAT) (present under the skin and abdominal area) Ibrahim, 2010).…”

Section: Introductionmentioning

confidence: 99%

Cardiorespiratory Fitness and Leg Muscle Power in Relation to Abdominal Adipose Tissue in Adolescents

Musa

Toriola

Abubakar

et al. 2023

IJKSS

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Background: Abdominal adiposity is associated with high risk of cardiometabolic diseases. Waist circumference has been used as a surrogate measure of abdominal adipose tissue in both youth and adults. Objectives: The present study evaluated whether cardiorespiratory fitness and leg power (LP) were independently associated with abdominal adipose tissue in 12-16-year-old Nigerian adolescents. Methods: This cross-sectional study comprised 2047 (1087 girls and 960 boys) adolescents who were evaluated for cardiorespiratory fitness and leg power. The cardiorespiratory fitness and leg power were assessed using the progressive cardiovascular endurance run (PACER) test and the vertical jump (VJ) test, respectively. Abdominal adiposity was evaluated with the waist circumference (WC). Regression models controlling for age and maturity status were used to assess the association of fitness and LP with WC. Results: Low leg power had significant negative association with the risk of abdominal adiposity in both girls (β=-0.307; p0.001) and boys (β=-0.262; p0.001). The observed relationship was independent of fitness, whereas the relationship between fitness and risk of abdominal adiposity was partly determined by leg power. Conclusion: Leg power and fitness were independently associated with the risk of abdominal adiposity in adolescents, but the association of leg power was stronger in girls. Health promotion efforts targeting reduction of abdominal adipose tissue should also include muscular power training type activities in addition to endurance-related activities.

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“…[ 9 ] Healthy changes in lifestyle and diet (as using functional foods and bioactive nutrients) are recommended as strategies to combat MetS. [ 10 11 ]…”

Section: Introductionmentioning

confidence: 99%

Effect of fermented camel milk on glucose metabolism, insulin resistance, and inflammatory biomarkers of adolescents with metabolic syndrome: A double-blind, randomized, crossover trial

et al. 2018

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Background:This study, for the first time, aimed to assess the effects of fermented camel milk (FCM) on glycemic and inflammatory parameters related to metabolic syndrome (MetS), an aggregation of cardiometabolic risk factors, in adolescents.Materials and Methods:In a double-blind, randomized crossover trial, overweight/obese adolescents (fulfilling MetS criteria, aged 11–18 years) were randomly assigned to receive FCM 250 cc per day for an 8-week period, a 4-week washout, and then diluted cow's yogurt (DCY) 250 cc/day for another 8-week period, or the reverse sequence. Fasting blood sugar (FBS), fasting insulin, insulin resistance by three equations, incretin hormone glucose-dependent insulinotropic peptide (GIP), and glucagon-like peptide-1 (GLP1) as well as inflammatory markers such as interleukin 6 (IL6) and tumor necrosis factor-alpha (TNF-α) were measured before and after each of the four periods. A 3-day food record and physical activity questionnaire were completed before each period. Statistical analyses were done using Minitab and SPSS software considering the significance level of 0.05.Results:Twenty-four participants with a mean (standard deviation) age of 13.77 (1.87) years (range: 10.45–16.25 years) (58% girls) completed the study. It resulted in nonsignificant mean reduction in IL6 (−18.28 pg/mL [95% confidence interval [CI]: −47.48; 10.90]; P = 0.20) and nonsignificant increase in glucose metabolizing hormones such as GIP (683.10 pg/mL [95% CI: −457.84; 1824.0]; P = 0.22) and GLP1 (6.98 pg/mL [95% CI: −66.61; 80.57]; P = 0.84) by FCM consumption in comparison to DCY. Nonsignificant decrease was observed in TNF-α in the first periods of the study. The changes of FBS, fasting insulin, and insulin resistance indices were not statistically significant as well.Conclusion:According to preliminary positive influences of FCM on inflammatory markers, and findings related to glucose metabolism, we suggest conducting further studies on its clinical impacts.

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A systematic review on the association of serum selenium and metabolic syndrome

Cited by 18 publications

References 49 publications

Blood Trace Element Concentrations in Polycystic Ovary Syndrome: Systematic Review and Meta-analysis

Blood Trace Element Concentrations in Polycystic Ovary Syndrome: Systematic Review and Meta-analysis

Cardiorespiratory Fitness and Leg Muscle Power in Relation to Abdominal Adipose Tissue in Adolescents

Effect of fermented camel milk on glucose metabolism, insulin resistance, and inflammatory biomarkers of adolescents with metabolic syndrome: A double-blind, randomized, crossover trial

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