Background and aims: A personal indirect calorimeter allows everyone to assess resting and non-resting energy expenditure, thus enabling accurate determination of a person's total calorie need for weight management and fitness. The aim of this study is to compare the performance of a new personal metabolic rate tracker based on indirect calorimetry, Breezing ® , with the Douglas bag method, the gold standard method for energy expenditure (EE) measurement.
Methods:Energy expenditures (EE) at rest and during activities, and respiratory quotient (RQ) were measured for 12 healthy subjects, including 7 male and 5 female under different living conditions. A total of 314 measurements were performed with Breezing ® , and the results were compared with those by the Douglas bag method.Results: R-squared correlation coefficients (R 2 ) between the data obtained with Breezing ® and the Douglas bag method were 0.9976, 0.9986, 0.9981, and 0.9980, for VO 2 , VCO 2 , EE, and RQ respectively.
Conclusions:The EE and RQ values determined by Breezing ® are in good agreement with those by the Douglas bag method.method. Over 300 measurements with human objects were performed following the instructions of the mobile indirect calorimeter and standard protocols of the Douglas Bag method. Statistical analysis methods, such as linear regression and Bland-Altman plot were used to establish quantitative correlation between of the values from the mobile indirect calorimeterand that from the gold standard method.
Materials and Methods
SubjectsTwelve healthy adults from Arizona State University (ASU), including 7 male and 5 female, were tested during this study. Their ages ranged from 21 to 38 years and their body mass indices (BMI) ranged from 16.9 to 32.2kg/m 2 (Table 1 and Table 2). The study was approved by the Institutional Review Board of Arizona State University (IRB protocol #1012005855) and all subjects participated in the study voluntarily, providing written informed consent prior to participation. The study was carried out at ASU from January 2013 to June 2014.
The mobile indirect calorimeter, Breezing ® DeviceThe Breezing ® device uses a sensor cartridge and a flow meter to determine the rate of consumed oxygen and produced carbon dioxide in the breath. The sensing technology of the new indirect calorimeter, which used a cell-phone camera as the optical detector, was previously reported [8]. The current Breezing ® device uses a QR code to carry calibration parameters of a single-use sensor cartridge, which can be scanned and recognized by the mobile application (app). The device is 6.0 oz. (170 g), and 1.8 in × 2.1 in × 4.8 in (4.7 cm × 5.4 cm × 12.3 cm), and connects wirelessly to an iOS mobile device, using Bluetooth 4.0 technology.