A Trial of Psychopharmacologic Measurement with Projective Techniques

Content analysis of speech samples to determine effect of lorazepam on anxiety

“…Anxiety scores previously obtained by this method correlate significantly with clinical psychiatric ratings of anxiety, with increase in systolic blood pressure, de-crease in skin temperature, higher plasma free fatty acid levels in fasting subjects, and greater anxiety scores found in the content of dreams when plasma free fatty acids are elevated. 7 Previous psychopharmacologic studies using this content analysis method have demonstrated that sedative doses of amobarbital ( 65 mg.) decrease anxiety scores significantly, 8 as do chlordiazepoxide ( 20 mg. 3 and perphena-zine5 ( 16 to 24 mg. per day). On the other hand, the antidepressant, imipramine ( 100 to 300 mg. per day) in nondepressed patients increased anxiety scores.…”

Profiles of children's psychological states derived from the Gottschalk-Gleser content analysis of speech

“…The affect scores of anxiety and hostility are very sensitive to many conditions, for example, the passage of time (see the generalizability studies of Gottschalk and Gleser, 1969, pp. 59-67); phases of the menstrual cycle (Gottschalk et al, 1962;Ivey and Bardwick, 1968;Sflbergeld et al, 1971); increases in serum dopamine beta-hydroxylase (Sflbergeld et al, 1975); different interviewers (Gottschalk and Gteser, 1969;Gottschalk, 1971;Schofer et al, 1978); various psychoactive drugs, such as perphenazine (Gottschalk et aL, 1960), amytal (Ross et al, 1963), chlordiazepoxide (Gleser et al, 1965;Gottschalk and Kaplan, 1972), and lorazepam (Gottschalk et al, 1972a); sex (Gottschalk and Gleser, 1969); and aging (Gottschalk and Gleser, 1969).…”