Visual object tracking is a fundamental task in the field of computer vision. Recently, Siamese trackers have achieved state-of-theart performance on recent benchmarks. However, Siamese trackers do not fully utilize semantic and objectness information from pre-trained networks that have been trained on the image classification task. Furthermore, the pre-trained Siamese architecture is sparsely activated by the category label which leads to unnecessary calculations and overfitting. In this paper, we propose to learn a Domain-Aware, that is fully utilizing semantic and objectness information while producing a class-agnostic using a ridge regression network. Moreover, to reduce the sparsity problem, we solve the ridge regression problem with a differentiable weighteddynamic loss function. Our tracker, dubbed DomainSiam, improves the feature learning in the training phase and generalization capability to other domains. Extensive experiments are performed on five tracking benchmarks including OTB2013 and OTB2015 for a validation set; as well as the VOT2017, VOT2018, LaSOT, TrackingNet, and GOT10k for a testing set. DomainSiam achieves a state-of-the-art performance on these benchmarks while running at 53 FPS.