2022
DOI: 10.1002/jcsm.13119
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A ubiquitous endocrine disruptor tributyltin induces muscle wasting and retards muscle regeneration

Abstract: Background Organotin pollutant tributyltin (TBT) is an environmental endocrine disrupting chemical and is a known obesogen and diabetogen. TBT can be detected in human following consumption of contaminated seafood or water. The decrease in muscle strength and quality has been shown to be associated with type 2 diabetes in older adults. However, the adverse effects of TBT on the muscle mass and function still remain unclear. Here, we investigated the effects and molecule mechanisms of low‐dose TBT on skeletal m… Show more

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