A Useful Method for the Dealkylation of Dialkyl Phosphonates

Adhesive properties onto galvanized steel plates of grafted poly(vinylidene fluoride) powders with phosphonated acrylates

“…Galvanized steel plates (Zn 86 g/m 2 , Cr < 15 mg/m 2 ) supplied by Cockerill Sambre (Liege, Belgium) were washed with diethyl oxide in an ultrasonic sound tray to remove grease and oil traces. Phosphonated acrylate monomers such as dimethyl(2‐acryloxyethyl)phosphonate (DAP) and its phosphonic acids derivatives (DAP monoacid and DAP diacid) were obtained using a simple synthetic method starting from commercial compounds 15–18. Acrylic acid (AAc) monomer stabilized with 0.02% hydroquinone monomethylether was used as obtained.…”

“…The synthesis of phosphonic acid monomer derivatives (DAP monoacid and DAP diacid) was performed in two steps, that is, silylation of a dimethylphosphonate function by BrSi(CH 3 ) 3 and then hydrolysis with an excess of methyl alcohol 15, 17, 18. By using an equivalent amount of brominated silane and DAP ( 1 ), a mixture of three functional phosphonated groups was obtained (DAP monoacid MDAP).…”

Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates

“…54,63 The crude reaction mixture was purified by column chromatography in silica gel with AcOEt/hexanes (50:50) to furnish diethyl 4-(chloromethyl)benzylphosphonate (5) as a colorless oil. Compound 5 (370 mg, 0.0013 mmol) was treated with TMSCl (0.50 mL, 0.0039 mmol) in dry acetonitrile at 0°C under N 2 atmosphere.…”

The Hydrolysis of Phosphinates and Phosphonates: A Review

“…Using lithium iodide, dialkyl phosphonates were cleaved under milder conditions [ 144 ]. In most of the cases, TMSBr was used in the dealkylations [ 145 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 166 , 167 , 168 , 169 , 170 , 171 ].…”