A Video Study of Drop Instillation in Both Glaucoma and Retina Patients with Visual Impairment

Hennessy, Amy; Katz, Joanne; Covert, David; Kelly, Colleen; Suan, Eric P.; Speicher, Matthew A; Sund, Newman J.; Robin, Alan L.

doi:10.1016/j.ajo.2011.05.015

Cited by 86 publications

(88 citation statements)

References 17 publications

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“…But patients with advanced glaucoma, by noticing some visual impairment, are more motivated to therapeutic adhesion; however, these patients have greater difficulty in self-administering eyedrops 10 . Such difficulty may be responsible for involuntary non-adhesion and not perceived by the patient, as suggested in recent studies of the capacity of eye-drop administration in patients with advanced glaucoma 11,12 . The correct placement of a droplet in the conjunctival fornix depends on several factors, such as the ability to see 13 and squeeze the bottle 14 or to detect whether the droplet has fallen in or out of the eye 15 .…”

mentioning

confidence: 88%

Difficulties of daily tasks in advanced glaucoma patients - a videotaped evaluation

Miguel

Fonseca²,

Oliveira³

et al. 2015

Revista Brasileira De Oftalmologia

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Objective: The purpose of this study was to perform an objective videotaped evaluation of the difficulties of eyedrop instillation and daily tasks in patients with advanced glaucoma with visual impairment. Methods: A prospective observational study was performed in advanced glaucoma patients with visual impairment, during 5 months. Patients completed a survey (with demographic questions, quality of life, compliance and eyedrop instillation) with interview and video recording in specific daily tasks (eyedrop instillation, climbing stairs, walking in a crowded room and in an irregular floor). Ophthalmologic evaluation was performed and its results registered in a form. Correlation was searched between limitation in quality of life, tasks' performance and visual fields. Results: 25 patients were included, corresponding to 12h of videotaping. All patients reported being capable of self-instilling eyedrops. 68% of them reported no difficulty instilling the eye drops at home, however 20% of the patients were unable to instill a drop in the eye in the objective evaluation. 72% of the patients stated never touching the eye with the bottle but 40% touched the ocular surface with the bottle. There was a moderate difficulty in the other tasks, with some patients exhibiting proprioceptive mechanisms of adaptation to impaired vision. There was a tendency of correlation between limitation in tasks and visual field defects, but no statistically significant. Conclusion: Patients with advanced glaucoma and visual impairment have marked difficulty in eye drop instillation and daily tasks, with a poor awareness of their inabilities. Some patients have proprioceptive adaptations that allow them to perform better than expected in tasks.Keywords: Glaucoma; Video recording; Quality of life; Patient compliance; Activity of daily living

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mentioning

confidence: 88%

Difficulties of daily tasks in advanced glaucoma patients - a videotaped evaluation

Miguel

Fonseca²,

Oliveira³

et al. 2015

Revista Brasileira De Oftalmologia

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“…Although papers evaluate instillation technique drops in patients with eye diseases, studies in almost its entirety, do not mention the literature used as reference to evaluate the technique [10][11][12][13][21][22][23][24][25][26]. According Vaidergorn et al, and Fraunfelder et al [27,28]instillation should be performed sitting or lying down, instilling eye drops only a single drop without contact from the bottle end with the ocular tissues.…”

Section: Discussionmentioning

confidence: 99%

“…Good part of the analyzed studies did not mention the practice scenarios where they were performed [10][11][12][13][14]. The literature suggests that research should be communicated in a transparent manner so that readers can follow the methodology and draw clear conclusions.…”

Section: Discussionmentioning

confidence: 99%

Technical Evaluation of Eye Drops Instillation: A Systematic Review

Souza¹,

Rezende²,

Silva³

et al. 2017

JPP

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Abstract:Objective: Assess the profile of eye drops in patients with eye diseases. Methods: Studies available in the scientific literature were identified without any time limits using the databases Embase-Medline, Scielo, Scopus and Web of Knowledge. The selected studies were compared with the following inclusion criteria: (i) if the study evaluated the eye drop instillation, (ii) if the study involved participation of patients with eye diseases. Results: Twelve studies met the inclusion criteria. Of them, 83.33% evaluated the technique of eye drop instillation in patients with glaucoma, 8.33% in patients with eye diseases and 8.33% in patients with cataract after undergoing surgery to correct. 41.66% of studies have chosen to record a video of patients to analyze the technique of instilling eye drops and 41.66% did not describe the/esearch location. Regarding the type of study, 75% had the design as prospective cross-sectional, 8.33% prospective open label study, 8.33% intervention study and 8.33% study called masked trial. Although studies evaluate the technique of eye drop instillation, only 8.33% describe in the article the reference in the literature used to evaluate patients. 50% of articles acknowledged some sort of bias or limitation. Conclusion: The limitations inherent in these types of studies should guide future research.

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“…5 Another recent study found that only about 9% of patients who use eye drops are able to properly self-administer them. 7 Thus, even if patients are reminded about taking their eye drop medication, there still exists a significant number of patients who fail to achieve eye drop delivery that follows their prescribed eye drop regimen.…”

Section: Introductionmentioning

confidence: 99%

“…However, it is well-known that compliance and getting the eye drop in the eye are significant problems. [1][2][3][4][5][6][7] Even in cases where a doctor has asked patients direct questions regarding eye drop regimen compliance, and electronic monitoring has been employed, drug delivery failure is still an issue. [8][9][10][11][12][13] Several devices have been developed to help patients adhere to and monitor eye drop regimens, [12][13][14][15] although none of these techniques for monitoring compliance are meant to determine whether the drops get into the eye; rather they measure if a patient attempts to administer the eye drops.…”

Section: Introductionmentioning

confidence: 99%

A novel eye drop application monitor to assess patient compliance with a prescribed regimen: a pilot study

Eaton

Gordon

konowal³

et al. 2015

Eye

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Purpose To assess the ability of a novel imaging device to allow physicians to personalize therapeutic regimens based on objective patient drop administration data. Methods A novel imaging system was used to record video of the drop technique of subjects in clinic (n = 25) or at home (n = 17) for 1 week. Video assessment by a reading center was compared with patient reporting and their prescribed regimen with respect to how many drops were applied and how many landed in the eye. Results Reading center assessment of both drops dispensed and drops landing in the eye was significantly different from the prescribed regimen in the clinic (P d = 0.005, P i o0.001, respectively) and at-home arms (P d = 0.003, P i o0.001, respectively). Conclusions This imaging system is a powerful tool to help physicians tailor patient therapy more accurately, to help researchers evaluate new drop therapies with objective rather than subjective data, and to potentially facilitate better patient training for improved drug delivery.

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A Video Study of Drop Instillation in Both Glaucoma and Retina Patients with Visual Impairment

Cited by 86 publications

References 17 publications

Difficulties of daily tasks in advanced glaucoma patients - a videotaped evaluation

Difficulties of daily tasks in advanced glaucoma patients - a videotaped evaluation

Technical Evaluation of Eye Drops Instillation: A Systematic Review

A novel eye drop application monitor to assess patient compliance with a prescribed regimen: a pilot study

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