A waterborne outbreak involving hepatitis A virus genotype IA at a residential facility in the Republic of Korea in 2015

Shin, Eunkyung; Kim, Jin Seok; Oh, Kyunghwan; Oh, Sung Suck; Kwon, MunJu; Kim, Soojin; Park, Jungsun; Kwak, Hyo‐Sun; Chung, Gyung Tae; Kim, Chul-Joong; Kim, Junyoung

doi:10.1016/j.jcv.2017.07.006

Cited by 23 publications

(14 citation statements)

References 12 publications

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“…Subsequently, 50 viral foodborne outbreaks and 1,211 patients have been reported annually (2012 to 2018) by the Ministry of Food and Drug Safety in Korea [ 25 ]. Furthermore, Korea has reported frequent HAV, RotaV, AdenoV, and AstroV outbreaks [ 26 , 27 , 28 ]. Although groundwater contamination by HuNoV and HAV was confirmed as the cause of several outbreaks in Korea [ 29 , 30 ], the prevalence of foodborne viruses in reservoirs in Korea has not been previously reported.…”

Section: Introductionmentioning

confidence: 99%

Effects of Weather and Environmental Factors on the Seasonal Prevalence of Foodborne Viruses in Irrigation Waters in Gyeonggi Province, Korea

et al. 2020

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This study aimed to investigate the prevalence of foodborne viruses in reservoirs (an important resource of irrigation water) and its correlation with environmental and weather factors. From May 2017 to November 2018, we visited ten reservoirs and a river in the Anseong region of South Korea and collected a total of 192 samples in accordance with the environment protection agency guidelines. We recorded the weather factors (temperature, humidity, and accumulated precipitation) and investigated the surrounding environment factors (livestock, fishing site, the catchment area of reservoirs, etc.). Our research results show that from the river and reservoirs, the detection rates of human norovirus GII, adenovirus, rotavirus, human norovirus GI, and astrovirus were 27.1, 10.4, 10.4, 4.16, and 3.1%, respectively. Their viral load ranged from −1.48 to 1.55 log10 genome copies/l. However, hepatitis A virus was not detected in any irrigation water sample. Although no sampling was performed in winter, foodborne viruses and male-specific coliphages were frequently found during spring (40.78%) and autumn (39.47%). Interestingly, the significant correlation between the accumulative precipitation and the number of detected norovirus and adenovirus was confirmed by linear regression analysis. Furthermore, when the accumulative precipitation ranged from 20 to 60 mm, it significantly affected the viral load and prevalence. Among the environmental factors, recreational facilities such as fishing sites and bungalow fishing spots were identified as contamination sources by correlation analysis. Our research results confirmed the correlations between environmental contamination factors in the reservoir and weather factors with the prevalence of foodborne viruses in the reservoir. These facilitates the assessment of potential foodborne virus contamination during crop irrigation. In addition, predictive models including environmental and weather factors should be developed for monitoring and controlling the safety of irrigation waters in reservoirs.

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Section: Introductionmentioning

confidence: 99%

Effects of Weather and Environmental Factors on the Seasonal Prevalence of Foodborne Viruses in Irrigation Waters in Gyeonggi Province, Korea

et al. 2020

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“…RNA do vírus da Hepatite A, embora pesquisado, ainda não tinha sido identificado em águas superficiais portuguesas usadas para a produção de água para consumo (Teixeira et al 2020) mas já tinha sido detetado nesta matriz nos Estados Unidos, Brasil, Espanha e República da Coreia (Jiang & Chu 2004, López Gálvez et al 2016, Shin et al 2017. Em águas para consumo, este vírus ainda não foi detetado em Portugal, mas já foi encontrado em água da rede de abastecimento da Colômbia (Peláez Carvajal et al 2016).…”

Section: Deteção De Rna Viral Por Rt-qpcrunclassified

Deteção de vírus entéricos em amostras de água natural superficial e de água para consumo humano

Salvador¹,

Caeiro²,

Aguilar³

et al. 2020

A&R

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Water-related infectious diseases are important causes of morbidity and mortality. Enterovirus and Hepatitis A and E viruses are, among others, representative of the enteric viruses, which are disease-causing agents mainly transmitted by the oral-fecal route, through water. The objective of this study is to search for enteric viruses by reverse transcription followed by Real-time PCR (RT-qPCR), in samples of natural surface water and in drinking water. It is also intended to evaluate the eventual association of these viruses with other fecal contamination indicators, and the efficacy of the water treatment plants in their elimination. It was confirmed the adequacy of the methodology implemented since, in the 15 samples analyzed so far, Hepatitis A virus and Enterovirus RNAs were detected in natural surface water samples, in two and three samples, respectively. Both viruses RNAs were detected in one of these samples. No viral nucleic acids were detected in drinking water samples. Fecal coliforms (microbial indicators of fecal contamination) were detected in natural water samples, but not in drinking water samples. Viral RNA and coliform detection only partially co-occurred.

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“…Hepatitis A virus (HAV) infection, which is a major cause of acute hepatitis, poses an important public health problem worldwide (1)(2)(3). The virus can spread through the faecal-oral route, e.g.…”

Section: Introductionmentioning

confidence: 99%

Molecular epidemiology of hepatitis A outbreaks in two districts in Indonesia in 2018: Same subtype, but different strains

Setyowati

Mubawadi²,

Mirasa³

et al. 2019

biom rep

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The present study aimed to analyse molecular epidemiological data from hepatitis A virus (HAV) outbreaks in two affected areas. The association between the knowledge of hepatitis A and incidence of infection was also determined. Serum samples were obtained from 88 individuals with clinical manifestations of acute hepatitis in Lamongan (n=54) in January 2018 and Bangkalan (n=34) in March 2018. The outbreak investigation was started one day after the outbreaks were reported by the Public Health Offices in Lamongan and Bangkalan. Anti-HAV immunoglobulin M (IgM) and PCR amplification products of the VP1 capsid protein-P2A protease and VP1-VP3 junctions were analysed. Positive PCR products were sequenced, and a phylogenetic tree was constructed using Molecular Evolutionary Genetics Analysis X software. The control group comprised healthy students and staff members from the two affected areas. Thus, 172 responses from the control and hepatitis A case groups were analysed to assess the association between the students' knowledge level and the incidence of HAV infection. A total of 32 (59.25%) of the 54 individuals from Lamongan and 19 (55.9%) of the 34 participants from Bangkalan were positive for anti-HAV IgM; 26 PCR tests were positive in the VP3-VP1 and/or VP1-P2A junction, which were identified as HAV subgenotype IA. The subtype of HAV in the two areas was IA, similar to those identified previously, but the viruses did not originate from the same strain, as identified by multiple alignment. The knowledge level of the students and staff members in Lamongan studying and working at a half-day school exhibited a significant association with the incidence; however, no association was observed among the students in Bangkalan studying at a full-day school with a dormitory.

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A waterborne outbreak involving hepatitis A virus genotype IA at a residential facility in the Republic of Korea in 2015

Cited by 23 publications

References 12 publications

Effects of Weather and Environmental Factors on the Seasonal Prevalence of Foodborne Viruses in Irrigation Waters in Gyeonggi Province, Korea

Effects of Weather and Environmental Factors on the Seasonal Prevalence of Foodborne Viruses in Irrigation Waters in Gyeonggi Province, Korea

Deteção de vírus entéricos em amostras de água natural superficial e de água para consumo humano

Molecular epidemiology of hepatitis A outbreaks in two districts in Indonesia in 2018: Same subtype, but different strains

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