A CEDS™ (Clock Embedded Differential Signaling) interface for the next generation TFT‐LCD applications is proposed. The proposed intra‐panel interface reduces the number of signal lines in the TFT‐LCD panel by embedding the clock signal in transmitted data without explicit clock lines, and it provides low EMI, low power consumption and high data rate. The CEDS protocol provides an embedded clock recovery scheme which is based on the delay‐locked loop (DLL). The CEDS interface is verified on a 42‐inch full‐HD (1920×1080) TFT‐LCD panel with the 10‐bit RGB and 120Hz driving technology. The maximum data rate is measured as higher than 1.405Gb/s, with a pixel clock frequency of up to 330MHz.