A collisionslly induced dissociation study of adamantane, 1-nitroadamantane, 1,3-dinitroadamantane and 1,3,5,74etranitroadamantane was carried out using tandem high-resolution mass spectrometry. Fragmentation pathways of the compounds were determined in the electron impact mode. It was found that the kagmentation of all three nitroadamantanes begins with the consecutive losses of the NO, groups followed by fragmentation of the hydrocarbon structure.