A Yeast Glycolipid Biosurfactant, Mannosylerythritol Lipid, Shows Potential Moisturizing Activity toward Cultured Human Skin Cells: The Recovery Effect of MEL-A on the SDS-damaged Human Skin Cells

Biosurfactants and Bioemulsifiers Biomedical and Related Applications – Present Status and Future Potentials

“…The diacetylated MEL (MEL-A) produced from soybean oil significantly increased the viability of the fibroblast and of the papilla cells over 150% compared with that of control cells, suggesting potential use as new hair growth agent stimulating the papilla cells. Using a three-dimensional cultured human skin model, Morita et al, (2009b) observed that the viability of the SDS damaged cells was markedly improved by the addition of MEL-A in a dose-dependent manner. This demonstrated that MEL-A also had a ceramide-like moisturising activity toward the skin cells.…”

Nitrogen Source Affects Glycolipid Production and Lipid Accumulation in the Phytopathogen Fungus <i>Ustilago maydis</i>

“…They are secreted into the extracellular media at the stationary phase when nitrogen becomes an environmental limitation [3]. Their surfactant properties make this type of glycolipids very promising for commercial production in cosmetic and pharmaceutical industry [4]- [6]. In recent years, several reports described enhanced yields of these biosurfactants when U. maydis cells are grown in yeast hydrolysates, urea and nitrate or ammonium salts, as nitrogen sources, and using also multiple carbon sources such as glucose, sucrose, lipids and glycerol [7]- [9].…”

Application of Yeast Glycolipid Biosurfactant, Mannosylerythritol Lipid, as Agrospreaders

“…To date, MELs are one of the most promising biosurfactants 5 9 because they have excellent surface-active and self-assembling properties, as well as versatile biochemical actions 5,7 . We recently demonstrated that MELs show a ceramide-like moisturizing activity toward human skin cells 10 , cell activating properties toward fibroblast and papilla cells 11 , and hair care properties 12 . Taking these functions into consideration, a MEL Abstract: The spreading property of mannosylerythritol lipids (MELs) was investigated in connection with our search for new application in agriculture.…”