A Young Male with a Non-ST Elevation Myocardial Infarction and Polycythemia Vera

Abstract

Polycythemia Vera (PV) is a clonal myeloproliferative disease characterized by an erythroid dominant trilineage proliferation of hematopoietic precursor cells. Acute coronary syndrome is known to occur in patients with PV. However, there are very rare reported cases of myocardial infarction upon the initial presentation of PV. We present such a case of a 37 years old male, with no known cardiovascular risk factors, who had an initial presentation of NSTEMI treated with drug eluting stent (DES). Later investigations revealed a diagnosis of Polycythemia Vera. Treatment strategies for MI in cases of myeloproliferative disease lacking clear guidance, further studies are needed in this matter.

Polycythemia Vera With Atrial Fibrillation: A Case Report and Review of the Literature

“…Another report by Malak et al concluded that 4% of all patients with myeloproliferative disorder die from MI [5]. Cardiac challenges in patients with PV include MI, in-stent restenosis [6], and progressive ischemic heart failure [7]. Atrial fibrillation (A-fib) is the most prevalent sustained arrhythmia, affecting up to 1% of the world's population [8].…”