Polycythemia vera (PV) is a myeloid stem cell disorder characterized by excess red cell mass. The two major complications of PV are thrombosis and bleeding. Atrial fibrillation is a potentially devastating condition that can complicate the course of PV. We describe a case of a 65-year-old woman with PV who presented with new-onset atrial fibrillation. The atrial fibrillation was aborted successfully, and the patient was started on oral anticoagulation with rivaroxaban. PV with atrial fibrillation poses a challenge in management due to the risk of thrombosis and bleeding. Despite the lack of standard recommendations or guidelines, this case highlights that oral anticoagulation therapy can be safe and convenient for such patients.

BackgroundThe present study was conducted to assess the renal effects of high dose versus low dose lisinopril in patients with diabetic nephropathy.

This article is an effort to reflect the role of media required to be played in the proper implementation of national youth policy in Pakistan. During a time of emergent numbers of problems and inadequate resources, Pakistan consider that the essence of promising future is to prepare youth to take on responsibilities and be socially, economically and politically empowered. But of course, for this huge mission a detail strategic plan and proper implementation is required that links framework and action plans for all youth and relevant stakeholders. While there are many other stakeholders connected with national youth policy, media is one stakeholder in this article, drawing our most attention. As the world is now moving towards globalization, we have witnessed the era of emerging trends. For example today the focus is more on knowledge based economies and social and economic networking, technology has been changed and is growing with the fast pace. This resulted in some different eco and social challenges. All around the globe, youth is actively involved in policy making because they know the growing challenges and changing environment better than the other age related segments. Considering the above point in mind, the author feels if the potential of youth is properly harnessed like in other countries, then this can bring a socio-economic revolution in Pakistan. On the contrary, if youth issues and ideas are not taken into consideration while policy making, this may result into one of the biggest challenge for the management in Pakistan in future. The young minds are needed to be shaped in a manner that they can live a better life with promising future and can benefit the whole society. With the ever changing circumstances, the growth and change in economy is constant. The rules and regulations regarding youth policies are needed to be implemented at national as well as provincial level, otherwise the nation has to face the serious outcomes in longer run. The increasing joblessness, among educated and uneducated youth will have negative impact on both economic and social life at individual and national level. The competition in economy is growing tough, far more educated youth now takes job for which they are overqualified. On the other hand, uneducated people can’t seem to move up in the lifestyle ladder. This causes social disintegration, which results in poverty aggravation. This requires all related stakeholders to be responsible in implementation of youth policy across the nation.