Ab interno canaloplasty (ABiC)—12-month results of a new minimally invasive glaucoma surgery (MIGS)

Davids, Anja‐Maria; Pahlitzsch, Milena; Boeker, Alexander; Winterhalter, Sibylle; Maier-Wenzel, Anna-Karina; Klamann, Matthias K. J.

doi:10.1007/s00417-019-04366-3

Cited by 31 publications

(32 citation statements)

References 23 publications

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“…4,11 In studies of canaloplasty, IOP reductions of 30-41% and medication reductions of up to 89% have been reported. [29][30][31] In our study mean IOP decreased a modest amount between Month 1 and Months 3 and 6 while the proportion of patients medication-free showed a corresponding increase suggesting that effectiveness may increase with time. While we cannot determine the reason for this with certainty, we can speculate that the trends are related to standard post-op steroid use.…”

Section: Discussionsupporting

confidence: 46%

Canaloplasty and Trabeculotomy Combined with Phacoemulsification in Open-Angle Glaucoma: Interim Results from the GEMINI Study

Gallardo¹,

Sarkisian²,

Vold³

et al. 2021

OPTH

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Section: Discussionsupporting

confidence: 46%

Canaloplasty and Trabeculotomy Combined with Phacoemulsification in Open-Angle Glaucoma: Interim Results from the GEMINI Study

Gallardo¹,

Sarkisian²,

Vold³

et al. 2021

OPTH

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“…In conclusion, modern surgeries are focused on minimising injuries and instrumentation, as well as shortening surgery time (i.e. ab interno canaloplasty 23 or flap-sparing canaloplasty 17 ). The mini-canaloplasty technique is a non-penetrating procedure that attempts to perform canaloplasty without simultaneous deep sclerectomy and cutting out deeper layers under the superficial scleral flap.…”

Section: Discussionmentioning

confidence: 99%

Mini-canaloplasty as a modified technique for the surgical treatment of open-angle glaucoma

Rękas

Konopińska

Byszewska

et al. 2020

Sci Rep

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Authors present a modified surgical technique for canaloplasty without preparing the classical trabeculo-Descemet's membrane (TDM) and having to close sutures. Twelve patients with open-angle glaucoma (OAG) (aged 58-77 years) received the modified technique, which does not require the deep scleral flap to be excised, an intrascleral lake to be created, or TDM dissection. After accessing the Schlemm's canal (SC), cannulation and placement of the sutures are made similar to those in the classical canaloplasty. The conjunctiva is closed via bipolar diathermy. The mean intraocular pressure (IOP) before surgery was 18.0 ± 8 mmHg, and the mean number of anti-glaucoma medications taken was 3 ± 1. Mean IOP at the end of the observation period (18.0 ± 6.0 months) was reduced by 23% (15.5 ± 4.1 mmHg), while the mean number of medications taken was reduced to 0.25 ± 1.0. In all eyes, the SC was successively opened, with no cheese-wiring. Adverse events included microhyphaema, mild corneal oedema, and folds in the TDM. The eyes recovered spontaneously within a few days after the procedure. The mini-canaloplasty technique may reduce the risk of complications associated with classical canaloplasty while effectively lowering the IOP in patients with OAG.

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“…Aus weiteren Publikationen geht eine ähnliche drucksenkende Wirkung der AbiC hervor. Nach einem Beobachtungszeitraum von 1 Jahr konnten Gallardo et al [7] eine Senkung des IOD um 32,3 % verzeichnen, Davids et al [8] um 28,1 % ± 14 und Ondrejka und Körber [8] sogar um 41 %. Letztere verwendeten hierzu nicht den iTrack, sondern das VISCO360-System (VISCO360 Viscosurgical System, Sight Sciences, Inc. Menlo Park, CA, USA).…”

Section: Diskussionunclassified

“…Dass das Auftreten einer postoperativen Vorderkammerblutung keine Seltenheit darstellt, schildern auch die o. g. Autoren in ihren Publikationen [3,5,7,9]. Davids et al verzeichneten sogar bei allen behandelten Augen (100 %) ein postoperatives Hyphäma [8]. Die Entstehung eines postoperativen Hyphämas scheint mit Angaben von 21,9 % [13], 23,7 % [14] und fast 50 % [15] auch bei der Kanaloplastik ab externo die häufigste Komplikation zu sein.…”

Section: Untersuchungszeitpunktunclassified

Canaloplasty ab interno (AbiC) – 2-Year-Results of a Novel Minimally Invasive Glaucoma Surgery (MIGS) Technique

Kazerounian

Zimbelmann

Lörtscher

et al. 2020

Klin Monbl Augenheilkd

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Purpose The aim of this study is to evaluate the long-term efficacy of a novel minimally invasive glaucoma surgery technique (MIGS), Ab interno Canaloplasty (AbiC). Material and Methods For this retrospective cohort study, we analysed the data of 25 eyes of 23 patients with open angle glaucoma who underwent an AbiC (6 eyes) or in case of an additional cataract, a combined cataract-AbiC procedure (“phacocanaloplasty ab interno”, 19 eyes), respectively. Postoperatively, we investigated the intraocular pressure (IOP) and the number of still required IOP-lowering medication, as well as surgery-related complications. Results Overall, the mean baseline IOP of 20.24 mmHg ± 5.92 (n = 25) was reduced to 10.64 mmHg ± 2.77 (n = 25, p < 0.001), 12.55 mmHg ± 3.33 (n = 22, p < 0.001) and 13.67 mmHg ± 2.15 (n = 21, p < 0.001) at 1 day, 1 year and 2 year follow-up visit, respectively. Compared to baseline, this implies a reduction in IOP of 47.4, 37.9 and 32.5%. An average glaucoma medication usage of 1.92 ± 1.04 was registered at baseline visit and was reduced to 0,05 ± 0,23 after 2 years of follow-up. 80% of patients were off medication. In 5 eyes (20%) further antiglaucomatous eye drops or surgical treatment were administered. The only surgical complications were hyphema in 5 eyes (20%) and a localized peripheral detachment of the Descemetʼs membrane in one eye (4%) with no late sequelae. Conclusion AbiC performed independently or combined with cataract surgery seems to be a safe and effective MIGS-technique with good long-term regulation of IOP and low risk profile.

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Ab interno canaloplasty (ABiC)—12-month results of a new minimally invasive glaucoma surgery (MIGS)

Cited by 31 publications

References 23 publications

Canaloplasty and Trabeculotomy Combined with Phacoemulsification in Open-Angle Glaucoma: Interim Results from the GEMINI Study

Canaloplasty and Trabeculotomy Combined with Phacoemulsification in Open-Angle Glaucoma: Interim Results from the GEMINI Study

Mini-canaloplasty as a modified technique for the surgical treatment of open-angle glaucoma

Canaloplasty ab interno (AbiC) – 2-Year-Results of a Novel Minimally Invasive Glaucoma Surgery (MIGS) Technique

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