ABC of oxygen: Hyperbaric oxygen therapy

Leach, R. M.; Rees, P. J.; Wilmshurst, Peter

doi:10.1136/bmj.317.7166.1140

Cited by 335 publications

(270 citation statements)

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“…Örneğin Dziewierz ve ark. (9) Kardiyak hasarlanma mekanizması ne olursa olsun CO zehirlenme hastalarında kardiyak hasarlanma saptanması HBO tedavi endikasyonları arasındadır (12). Ancak pratik uygulamalarda STEMI saptadığınız hastalarda hem anjiyografinin ön plana geçmesi hem de hastanın anjiyografi sonrasında yüksek aritmi riski nedeniyle erken dönemde HBO uygulamasının güvenilirliğinin ve zamanlamasının belirsiz olduğunu düşünmekteyiz.…”

Section: Discussionunclassified

ST-Segment Elevation Myocardial Infarction Due to Carbon Monoxide Poisoning

Çorbacıoğlu¹,

Cikrikci²,

Çevik³

2015

JAEMCR

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Introduction: Carbon monoxide (CO) intoxications, which are often characterized by neurological and respiratory symptoms, are commonly encountered serious poisonings. However, in the literature, although cardiac complications due to poisoning are rarely mortal, conditions such as serious arrhythmias and myocardial infarction have also been reported. Cardiac evaluation and follow-up on CO poisoning is very important for reducing mortality. Case Report: In the present case, we report a ST-segment elevation myocardial infarction (STEMI) believed to be triggered by CO poisoning established in a 48-year-old male patient, whose medical history was unremarkable, admitted to the emergency department due to stove poisoning and chest pain complaint. Conclusion: Although myocardial ischemia is an expected clinical condition in CO intoxications, STEMI is rare. In general, though underlying coronary heart disease is detected on angiography of patients with STEMI due to CO poisoning, in this rare condition, coronary artery anatomy can be completely normal. JAEMCR 2015; 6: 46-8 DOI: 10.5152/jaemcr.2015 6: 46-8 DOI: 10.5152/jaemcr. .1013 Giriş Karbon monoksit (CO) zehirlenmeleri özellikle kış aylarında sık karşılaşılan ve ölümle sonuçlanabilen ciddi zehirlenmelerdir. CO, hemoglobine oksijenden daha yüksek bir afinite ile bağlanarak dokulara giden oksijen miktarının azalmasına neden olur. Dolayısıyla beyin ve kalp gibi oksijen ihtiyacı daha fazla olan organlarda zehirlenmeye bağlı komplikasyonlar daha sık görülmektedir (1). CO zehirlenmesinde genellikle nörolojik ve solunumsal semptomlar ön planda olmasına karşın daha nadir olarak kardiyomyopati, anjina atakları, myokard enfarktüsü, aritmi, kalp yetmezliği, kardiyojenik şok ve ani ölüm gibi kardiyak komplikasyonlarda literatürde bildirilmiştir (1).Bu vakada CO zehirlenmesinin daha nadir ancak ciddi bir komplikasyonu olarak; CO zehirlenmesinin tetiklediğini düşündüğümüz ST-segment elevasyonlu miyokard enfarktüsü (STEMI) geçiren bir hasta sunulmuştur. 46

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Section: Discussionunclassified

ST-Segment Elevation Myocardial Infarction Due to Carbon Monoxide Poisoning

Çorbacıoğlu¹,

Cikrikci²,

Çevik³

2015

JAEMCR

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“…The increased oxygen pressure raises the tissue-cellular oxygen diffusion gradient, causing tissue, and ultimately cellular oxygenation to improve [2]. The hyperoxia that occurs due to the use of a hyperbaric oxygen treatment makes this procedure effective when treating various types of medical conditions.…”

Section: Background and Importancementioning

confidence: 99%

Hyperbaric Oxygen Therapy of Ischemic Cranial Skin Flap: Case Report and Review of the Literature

Mesfin¹,

Burton²,

Massa³

et al. 2017

CRCM

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Hyperbaric Oxygen Therapy (HBOT) is a medical procedure and therapeutic modality that utilizes 100% oxygen. HBOT has been used various medical conditions such as progressive necrotizing fasciitis, peripheral arterial insufficiency, and diabetic wounds of the lower extremities. The case report reported here describes the usage of HBOT as an adjunctive "rescue" measure to salvage a patient's cranioplasty scalp flap after flap ischemia was noted 2 days post-operatively. Patient is a 54 year-old caucasian female who presented to our facility with symptoms of a left MCA infarct. CT and MRI of her brain revealed a left MCA infarct with hemorrhagic stroke with significant cerebral edema, and midline shift. She was taken to the operating room for a left decompressive hemi-craniectomy. She had cranioplasty utilizing native bone flap delayed fashion. She had wound infection after cranioplasty which required removal of native bone. After appropriate treatment for infection, she had cranioplasty utilizing prosthetic Biomet implant. Post-cranioplasty, patient developed ischemic cranial flap. This was recognized within 48 hrs and HBOT was implemented. She has a successful rescue of the ischemic cranial flap after she received 14 consecutive treatments over two weeks. In our knowledge, this is the first successful treatment of HBOT reported after prosthetic cranioplasty for scalp flap ischemia.

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“…The latter figure is sufficient to meet the needs of tissue oxygen extraction at rest, regardless of the adequacy of the oxygen bound by hemoglobin. The capacity of OHB to increase oxygen content and independently meet the oxygen needs of resting tissue has led to its use under conditions of compromised oxygen supply, such as deep anemia, carbon monoxide poisoning, and acute and chronic ischemia (Leach et al, 1998;Wattel et al, 1998;Hart et al, 1987;McLoughlin et al, 1999;Van Meter, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…HBO is more commonly used in conditions of tissue hypoxia or to treat decompression sickness and air embolism, in which gas bubbles obstruct blood flow (Gill & Bell, 2004). Therapeutic Functions for hyperbaric oxygen (Leach et al, 1998;Undersea & Hyperbaric Medical Society, 2005 Increasing oxygen delivery -Henry's Law states that the amount of a gas dissolved in solution is ideally directly proportional to its partial pressure. Therefore, the dissolved oxygen concentration in plasma of 0.3 ml/dl at sea level (1.0 atm) increases to 1.5 ml/dl after administration of 100 percent oxygen, while the hyperbaric oxygen delivered at 3.0 atm has a dissolved oxygen content of 6 ml/dl.…”

Section: Introductionmentioning

confidence: 99%

Improvement in Serum Anti-Müllerian Hormone Levels in Infertile Patients after Hyperbaric Oxygen (preliminary results)

Pineda

Ortiz

Moguel

et al. 2015

JBRA Assisted Reproduction

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Objective: To assess whether hyperbaric oxygen sessions elevate serum levels of anti-Müllerian hormone (AMH) in patients diagnosed with infertility with serum levels of less than or equal to 1 ng/dl AMH. Methods: A study was performed on 4 patients diagnosed with infertility. Serum AMH level was measured at the beginning and end of hyperbaric oxygen sessions, and endometrial thickness was measured on endometrial cycle day 14 before and during the hyperbaric oxygen sessions. Results: In two of the four patients, the serum AMH level increased by 40% and 116%. In one patient the serum AMH level was not elevated, with a serum AMH level before and after treatment of 0.1 ng/dl. The fourth patient became pregnant during the hyperbaric oxygen sessions. Endometrial thickness was not improved in any of our patients. Conclusions: This study showed that hyperbaric oxygen sessions can increase serum AMH levels, with a significant increase of 116% in one case. Therefore, this therapy can be used as an alternative treatment for patients with serum AMH levels of less than or equal to 1 ng/dl and a limited number of eggs for IVF cycles but not for patients with serum AMH levels of less than or equal to 0.1 ng/dl, as we did not observe an increase in serum AMH level in patients with an initial AMH level of 0.1 ng/dl. This study did not demonstrate improvement in endometrial growth following hyperbaric oxygen sessions.

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ABC of oxygen: Hyperbaric oxygen therapy

Cited by 335 publications

References 0 publications

ST-Segment Elevation Myocardial Infarction Due to Carbon Monoxide Poisoning

ST-Segment Elevation Myocardial Infarction Due to Carbon Monoxide Poisoning

Hyperbaric Oxygen Therapy of Ischemic Cranial Skin Flap: Case Report and Review of the Literature

Improvement in Serum Anti-Müllerian Hormone Levels in Infertile Patients after Hyperbaric Oxygen (preliminary results)

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