2002
DOI: 10.1007/s00261-001-0072-1
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Abdominopelvic tuberculosis simulating disseminated ovarian carcinoma with elevated CA-125 level: report of two cases

Abstract: We report the radiologic presentations of two cases of peritoneal-pelvic tuberculosis. The initial interpretation based on the adnexal masses, ascites, omental and peritoneal thickening, and elevated serum CA-125 levels led to an erroneous preliminary diagnosis of disseminated ovarian cancer. In both patients, histologic examination showed tuberculosis. The clinical and radiologic findings resolved significantly after several months of multidrug antituberculosis treatment.

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Cited by 33 publications
(23 citation statements)
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“…CA 125 is an important marker of gynaecologic malignancies, foremost ovarian cancer, but elevation of CA 125 level can be seen in some benign pathologies like endometriosis, pregnancy, adenomyosis and pelvic inflammatory disease (Sheth, 1996). CA 125 levels also arise in peritoneal tuberculosis, but decrease to normal range after the treatment of the disease (Thakur et al, 2001;Barutcu et al, 2002). As our patient had high CA 125 levels, there are many case reports of peritoneal tuberculosis with elevated CA 125 levels in the literature (Thakur et al, 2001;Corapcıoglu et al, 2006;Koc et al, 2006).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…CA 125 is an important marker of gynaecologic malignancies, foremost ovarian cancer, but elevation of CA 125 level can be seen in some benign pathologies like endometriosis, pregnancy, adenomyosis and pelvic inflammatory disease (Sheth, 1996). CA 125 levels also arise in peritoneal tuberculosis, but decrease to normal range after the treatment of the disease (Thakur et al, 2001;Barutcu et al, 2002). As our patient had high CA 125 levels, there are many case reports of peritoneal tuberculosis with elevated CA 125 levels in the literature (Thakur et al, 2001;Corapcıoglu et al, 2006;Koc et al, 2006).…”
Section: Discussionmentioning
confidence: 99%
“…The clinical and laboratory fi ndings of peritoneal tuberculosis can cause diffi culties in differential diagnosis. Because of abdominal pain and distension, weight loss, cystic or solid masses, ascites and elevated CA 125 levels, peritoneal tuberculosis usually mimickings ovarian cancer (Barutcu et al, 2002;Piura et al, 2002).…”
Section: Introductionmentioning
confidence: 99%
“…Ciò può avvenire anche in assenza di sintomi classici di infezione sistemica, come tosse, febbre o versamento pleurico [32]. L'ascite tubercolare rappresenta poco più dell'1% delle cause di ascite e viene diagnosticata con l'isolamento del Mycobacterium nel liquido ascitico (che richiede alcune settimane) e/o con la dimostrazione di granulomi caseosi o di bacilli alcol/acido resistenti nelle biopsie peritoneali, effettuate in corso di laparoscopia (l'accertamento considerato più conclusivo) o con la risposta dell'ascite al trattamento specifico [33][34][35][36]. I test più recenti, come l'amplificazione con PCR del DNA, consentono una diagnosi veloce, ma soffrono di scarsa sensibilità [37,38].…”
Section: Domande Da Porsiunclassified
“…The clinical features of TB peritonitis are nonspecific and include abdominal pain, fever, weight loss, and diarrhea. Elevated serum levels of cancer antigen (CA)-125 has been documented in this disease and was subsequently recommended as an indirect marker for disease progression (4)(5)(6). Herein, we describe a rare case of primary small intestinal NK/T-L that mimicked TB peritonitis.…”
Section: Introductionmentioning
confidence: 98%