Abflussdruck, Minutenvolumen und Widerstand der Kammerwasser-strömung des Menschen

Goldmann, H.

doi:10.1007/bf00143664

Cited by 150 publications

(42 citation statements)

References 48 publications

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“…Discussion The researches of Grant (1950Grant ( , 1951 and ourselves, with the electronic tonometer, show that most cases of ocular hypertension are due, totally or partially, to an increase of the resistance to the aqueous flow. Using another method, Goldmann (1951) reached the same conclusion.…”

Section: Resultssupporting

confidence: 53%

“…These criteria of classification, which are similar to those adopted by Goldmann (1951) and Duke-Elder (1952), differentiate congestive glaucoma from the non-congestive condition; in the latter, the irido-corneal angle is either narrow or wide, but never closed. The three main symptoms (hypertension, papillary excavation,-and perimetric defects) may progress independently of each other.…”

Section: R Weekers and E Prijotmentioning

confidence: 65%

“…According to Goldmann (1951), the flow of the aqueous humour from the anterior segment of the eye obeys relatively simple laws. Poiseuille's law can be applied: Pf R F is the flow of aqueous humour expressed in cmm.…”

Section: R Weekers and E Prijotmentioning

confidence: 99%

See 2 more Smart Citations

Measurement of the Resistance to the Aqueous Flow by the Electronic Tonometer : Results in Cases of Congestive Glaucoma before and after Treatment

Weekers¹,

Prijot²

1952

British Journal of Ophthalmology

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Section: Resultssupporting

confidence: 53%

Section: R Weekers and E Prijotmentioning

confidence: 65%

See 1 more Smart Citation

Measurement of the Resistance to the Aqueous Flow by the Electronic Tonometer : Results in Cases of Congestive Glaucoma before and after Treatment

Weekers¹,

Prijot²

1952

British Journal of Ophthalmology

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“…Using the relationship between the four parameters of aqueous humor dynamics, it also led to a development of methods of assessing aqueous humor outflow in in vivo settings. Grant developed a method of measuring the facility of aqueous humor outflow using a tonometer (Grant, 1950), and Goldman described methods for measuring three of its parameters; intraocular pressure, aqueous humor formation, and episcleral venous pressure (Goldman, 1951). The steady state equations used in such methods contained four parameters, and fourth could be calculated when the rest of the parameters could be determined via direct measurement.…”

Section: Uveoscleral Outflow Quantificationmentioning

confidence: 99%

A model to measure lymphatic drainage from the eye

Kim

Johnston

Gupta

et al. 2011

Experimental Eye Research

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Intraocular pressure (IOP) is the most important risk factor for glaucoma development and progression. Most anti-glaucoma treatments aim to lower IOP by enhancing aqueous humor drainage from the eye. Aqueous humor drainage occurs via well-characterized trabecular meshwork (TM) and uveoscleral (UVS) pathways, and the recently described ciliary lymphatics.The relative contribution of the lymphatic pathway to aqueous drainage is not known. We developed a sheep model to quantitatively assess lymphatic drainage along with TM and UVS outflows. Following intracameral injection of 125 I-bovine serum albumin (BSA), lymph and blood samples were continuously collected. Lymphatic and TM drainage were quantitatively assessed by measuring 125 I-BSA recovery. This quantitative sheep model enables assessment of relative contributions of lymphatic drainage (1.64% ± 0.89%), TM (68.86% ± 9.27%) and UVS outflows (19.87% ± 5.59%), and may help to better understand the effects of glaucoma agents on outflow pathways.iii DedicationThis thesis is dedicated to my parents and little brother for their love, endless support and encouragement.iv

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“…A decrease in outflow facility with age has been reported using tonography, fluorophotometry, and perfusion studies of normal eyes [50][51][52]. An approximately 30% decline in outflow facility has been observed in eyes <40 years of age (0.33 μl/min/mmHg) compared to >60 (0.23 μl/min/mmHg) [50,53].…”

Section: Aqueous Dynamics Of Laser Trabeculoplastymentioning

confidence: 94%

Laser Trabeculoplasty and Aqueous Dynamics

Lee¹,

Rahmatnejad²,

Waisbourd³

et al. 2016

Glaucoma - Intraocular Pressure and Aqueous Dynamics

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For the past four decades, laser trabeculoplasty has been a staple in the treatment armamentarium against glaucoma. Although the exact mechanism of laser trabeculoplasty has not been fully elucidated, its clinical utility in lowering intraocular pressure has been well established. Aqueous dynamic studies uniformly reveal an increase in aqueous outflow facility at the trabecular meshwork. Accumulating evidence suggests that the mechanism is the result of complex cellular and biochemical processes. Histopathological studies of the trabecular meshwork tissue after argon laser suggest an additional mechanical role. The traditional treatment algorithm for glaucoma placed laser trabeculoplasty as an intermediary between medical therapy and incisional surgery. However, because of the safety profile of selective laser trabeculoplasty, recent studies have challenged this treatment paradigm. One such study was a multicenter trial headed by our department that compared laser trabeculoplasty and medical therapy as initial treatment for glaucoma. We showed a similar efficacy between the two modalities, reinforcing the possibility of using laser as the initial treatment in the right clinical setting.

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Abflussdruck, Minutenvolumen und Widerstand der Kammerwasser-strömung des Menschen

Cited by 150 publications

References 48 publications

Measurement of the Resistance to the Aqueous Flow by the Electronic Tonometer : Results in Cases of Congestive Glaucoma before and after Treatment

Measurement of the Resistance to the Aqueous Flow by the Electronic Tonometer : Results in Cases of Congestive Glaucoma before and after Treatment

A model to measure lymphatic drainage from the eye

Laser Trabeculoplasty and Aqueous Dynamics

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