Abnormality of retinal arterial velocity profiles using Doppler Fourier-domain optical coherence tomography in a case of Takayasu's arteritis with aortic regurgitation

Tani, Tomofumi; Takahashi, Atsushi; Nagaoka, Taiji; Yoshida, Akitoshi

doi:10.1016/j.ajoc.2016.12.020

Cited by 6 publications

(6 citation statements)

References 3 publications

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“…Doppler optical coherence tomography system has been shown to enable the measurement of retinal microcirculation in patients with AR with Takayasu arteritis. Doppler optical coherence tomography showed the reflection of the changes in the circulatory system to the retina [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

Retinal Vascular Density Change in Patients With Aortic Valve Regurgitation

Topaloğlu

Bılgın

2023

Cardiol Res

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Background The aim of this study was to assess retinal vessel density in the superficial capillary plexus layer, deep capillary plexus layer and choriocapillaris plexus layer in patients with aortic valve regurgitation (AR) using optical coherence tomography angiography (OCTA). Methods Thirty-eight healthy participants (group 1) and 38 patients with AR (group 2) were assessed for this study. Diagnosis of AR is made by transthoracic echocardiography (TTE). Severity of AR was assessed according to values in the 2014 American Heart Association/American College of Cardiology (AHA/ACC) valve guideline. Superficial capillary plexus density (SCPD), deep capillary plexus density (DCPD) and choriocapillaris plexus density (CCPD) were analyzed between groups using OCTA. Results SCPD measurements were found to be decreased in the nasal, inferior and central regions of patients with AR (P ≤ 0.05). DCPD measurements were found to be decreased in the nasal and inferior regions of patients with AR (P ≤ 0.05). CCPD measurements were found to be decreased in the inferior and central regions of patients with AR (P ≤ 0.05). In patients with AR, CCPD measurements were significantly decreased in the inferior region compared to the control group. Central macular thickness was found to be significantly decreased in the patients with AR. Conclusions Patients with AR showed decreased flow density compared with healthy controls. Retinal perfusion measured using OCTA in patients with AR may give an idea about microperfusion.

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Section: Discussionmentioning

confidence: 99%

Retinal Vascular Density Change in Patients With Aortic Valve Regurgitation

Topaloğlu

Bılgın

2023

Cardiol Res

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“…43 In a case report, Tani et al demonstrated that Doppler Fourier-domain OCT (DOCT) may show parabolic retinal blood velocity profiles (RBVP) during the systolic phase and abnormal RBVP during the diastolic phase in a patient with TKA with aortic regurgitation. 44 These ocular imaging techniques could be used by ophthalmologists as screening tools to identify patients that may have TKA and for whom it may be worthwhile to consider applying the modified Ishikawa diagnostic criteria.…”

Section: Tka Signs and Symptomsmentioning

confidence: 99%

Large-Vessel Vasculitis in Ophthalmology: Giant Cell Arteritis and Takayasu Arteritis

Dhanani

Zhao

Charoenkijkajorn

et al. 2022

Asia-Pacific Journal of Ophthalmology

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Giant cell arteritis and Takayasu arteritis are large-vessel vasculitides that share multiple common features but also have significant differences in epidemiology, demographics, clinical presentation, evaluation, and treatment. Giant cell arteritis is more common in elderly patients of Caucasian descent versus Takayasu arteritis, which is more prevalent in younger patients of Asian descent. Although traditionally age has been the main criterion for differentiating the 2 etiologies, modifications in the diagnostic criteria have recognized the overlap between the 2 conditions. In this monograph, we review the diagnostic criteria for both conditions and describe the epidemiology, pathogenesis, histology, evaluation, and management for large-vessel vasculitis in ophthalmology. Additionally, we describe ocular imaging techniques that may be utilized by ophthalmologists to identify manifestations of large-vessel vasculiti- des in patients. Lastly, we compare and contrast the key clinical, laboratory, and pathologic features that might help ophthalmologists to differentiate the 2 entities.

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“…3 These patients have increased susceptibility to heart failure, strokes, myocardial infarctions, and transient ischemic attacks, which significantly increases mortality. 27 Strokes occur in 8.9% to 12% of patients that have Takayasu arteritis, and 3.4% experience myocardial infarctions. 24,28 A strong risk factor for increased morbidity is the presence of aortic valve regurgitation.…”

Section: Prognosismentioning

confidence: 99%

“…24,28 A strong risk factor for increased morbidity is the presence of aortic valve regurgitation. 27 Congestive heart failure is the leading cause of death in these patients. 3 The relapse rate of Takayasu arteritis is 50%.…”

Section: Prognosismentioning

confidence: 99%

“…29 Approximately 13-25% of patients with Takayasu arteritis develop aortic valve regurgitation, which is suspected in causing retinal hypoperfusion in early stages of Takayasu retinopathy. 27 As a result of vascular damage, neurological manifestations occur in up to 50% of patients. 30 Ocular complications for Takayasu retinopathy typically do not occur until stage 4.…”

Section: Complicationsmentioning

confidence: 99%

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Collateral Damage: A Differential of Takayasu Retinopathy

Duong

2020

CRO (Clinical &Amp; Refractive Optometry) Journal

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Background: Takayasu retinopathy is the ocular manifestation of Takayasu arteritis, a vasculitis affecting the aorta and aortic branches. Ocular manifestations are a result of cerebral and ophthalmic nonperfusion, and are noted in 8.1% to 68% of patients with Takayasu arteritis. Management of Takayasu retinopathy relies on treatment of the underlying systemic condition. Case Report: A 60 year old African American male was referred for a comprehensive eye exam after abnormal findings were noted on his diabetic teleretinal exam. Upon clinical examination, the patient was diagnosed with moderate to severe diabetic retinopathy, and a fluorescein angiography was ordered due to the presence of irregular vessels on the optic nerves. Takayasu retinopathy was considered as a differential diagnosis after review of the fluorescein angiography. Further work up with magnetic resonance angiography (MRA) showed no signs of significant stenosis. Conclusion: Takayasu retinopathy is a rare ocular manifestation that can aide in diagnosing a rare and previously undetected systemic disease of Takayasu arteritis. It is important for primary eye care providers to be assertive in performing additional diagnostic tests to prevent misdiagnosis and management of an underlying systemic condition. CE Notification: This article is available as a COPE accredited CE course. You may take this course for 1-hour credit. Read the article and take the qualifying test to earn your credit. Click here to Enroll (https://www.crojournal.com/collateral-damage-a-differential-of-takayasu-retinopathy) Please check COPE course expiry date prior to enrollment. The COPE course test must be taken before the course expiry date.

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Abnormality of retinal arterial velocity profiles using Doppler Fourier-domain optical coherence tomography in a case of Takayasu's arteritis with aortic regurgitation

Cited by 6 publications

References 3 publications

Retinal Vascular Density Change in Patients With Aortic Valve Regurgitation

Retinal Vascular Density Change in Patients With Aortic Valve Regurgitation

Large-Vessel Vasculitis in Ophthalmology: Giant Cell Arteritis and Takayasu Arteritis

Collateral Damage: A Differential of Takayasu Retinopathy

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