Abobotulinum toxin A for periorbital facial rejuvenation: impact on ocular refractive parameters

Eftekhari, Mohammad Hossein; Aghaei, Hossein; Kangari, Haleh; Bahrami, Milad; Eftekhari, Shervin; Tabatabaee, Seyed Mehdi; Shahraki, Kourosh; Bahrami, M.; Broumand, Mohammad Ghassemi

doi:10.1111/cxo.13117

Cited by 4 publications

(4 citation statements)

References 11 publications

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“…There are a variety of treatment options to mitigate the signs of periorbital skin aging, including topical retinoids, 13 radiofrequency, 14,15 broadband infrared, 16 intense pulsed light, 17 chemical peels, 18 botulinum toxin, 19 and platelet‐rich plasma (PRP), 5 and non‐ablative and ablative laser resurfacing procedures 15,20 . Full surface and fractional ablative resurfacing procedures are effective in improving periorbital wrinkles and laxity, but, because the epidermis is ablated, the recovery may take 1–2 weeks, and posttreatment erythema and hyperpigmentation commonly emerge, especially in darker skin types.…”

Section: Discussionmentioning

confidence: 99%

Treatment of periorbital wrinkles using thermo‐mechanical fractional injury therapy versus fractional non‐ablative 1565 nm laser: A comparative prospective, randomized, double‐arm, controlled study

et al. 2021

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Background: Non-ablative fractional laser is an effective modality for the treatment of periorbital wrinkling, one of the earliest signs of skin aging. Thermomechanical fractional injury (TMFI) therapy (Tixel ® , Novoxel ® , Israel) is an innovative technology that is now being used for facial skin rejuvenation. Our study compares the clinical results, side effects, and downtime profile between TMFI treatment and non-ablative fractional 1565 nm laser (ResurFX ® , Lumenis, Israel). METHODS: This was a prospective study of 68 patients (64 women, 4 men) with skin types I-VI in two medical centers (34 from Israel, 34 from the USA) that were randomized to receive either TMFI or NAFL treatment for periorbital wrinkling. Patients received 3-5 treatments, 3-5 weeks apart. Six months after the last treatment, the change in Fitzpatrick Wrinkling Classification System (FWCS) was calculated by three non-involved physicians and compared to pretreatment results. Side effects and downtime profiles were assessed in each group (including VAS pain assessment, time required to refrain from work and social activity, and time required for the resolution of redness, edema, and crusts.) RESULTS: A moderate improvement in periorbital wrinkling was demonstrated in both groups, with an average improvement of 1.6 ± 0.6 in FWCS in the TMFI group and an average improvement of 1.7 ± 0.8 in the NAFL group (p < 0.001). Postprocedural VAS score was 5.86 ± 2.3 in the NAFL group and 4.01 ± 2.6 in the Tixel ® group. Approximately 80% of subjects returned to both work and social activities two days postprocedure. Crusts were reported by 52% of patients in the TMFI group, compared to 16% of patients in the NAFL group more than 48 hours postprocedure (p < 0.05). There were no statistically significant differences in the other parameters between the two groups. CONCLUSION: TMFI is an effective and safe modality for the treatment of periorbital wrinkling, with comparable results to the 1565 nm NAFL.

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Section: Discussionmentioning

confidence: 99%

Treatment of periorbital wrinkles using thermo‐mechanical fractional injury therapy versus fractional non‐ablative 1565 nm laser: A comparative prospective, randomized, double‐arm, controlled study

et al. 2021

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“…As the depth increases, less stroma remains, and higher densities of the medicine can penetrate and accumulate in the anterior chamber [14]. The use of 0.02% Mitomycin C for 12 seconds to 2 minutes after superficial withdrawal was not toxic to endothelial cells due to the shallow depth of withdrawal [15,17].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Mitomycin C Effect on Corneal Endothelial Cell Density After Photorefractive Keratectomy

Shahraki

2023

JOJO

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Background: Photorefractive keratectomy (PRK) is a commonly performed surgical procedure for the correction of refractive errors, such as myopia. Mitomycin C (MMC) has been used as an adjunctive agent to modulate the healing response and reduce haze and fibrosis after PRK. However, the effect of MMC on corneal endothelial cell density, a crucial factor in maintaining corneal transparency and function, remains a subject of debate. This study aimed to evaluate the effect of intraoperative application of MMC 0.02% during PRK on corneal endothelial cell density.

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“…Most studies in Iran often focused on younger age groups, such as students (8). Although several studies in different regions of Iran have sought to investigate refractive errors in older populations (14,(20)(21)(22), they only included small proportions of the populations, and their findings cannot be generalized to people living in a specific region.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have found variations in refractive error frequency between different ethnic groups. On the other hand, most primary studies have been conducted on European or American populations (5,(8)(9)(10)(11)(12). Refractive error prevalence was reported to be more than 60% in people over the age of 40 years in some parts of Asia (13)(14)(15).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Refractive Errors and Associated Factors in the Population of the Eye Cohort Study in Southeast Iran

Shahraki,

Tahkor,

Shahraki Sanavi

et al. 2023

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Objectives: The study aims to determine the age- and sex-adjusted prevalence of refractive errors and its related factors among the adult population of southeastern Iran. Methods: The current study included 9280 individuals aged 35 to 70 years using a multistage random sample method from October 2015 to January 2019 as a part of a Persian cohort study in Zahedan. Uncorrected and corrected vision, objective noncycloplegic, and subjective refraction were measured, with all participants undergoing ophthalmoscopy, slit-lamp biomicroscopy, fundoscopy, refraction, and retinoscopy. Data were analyzed using SPSS version 23.0 statistic software and described as percentage, odds ratio, and 95% confidence interval. Comparisons between groups and relationships among risk factors and refractive errors were performed with chi-square, nominal, and multiple regression analysis. Results: The prevalence of low and moderate myopia, high myopia, low and moderate hyperopia, high hyperopia, low and moderate astigmatism, and high astigmatism was 24.2 (95% CI: 22.40 - 25.90), 1.5(95% CI: 0.00 - 3.53), 16.1(95% CI: 14.20 - 17.90), 1.3(95% CI: 0.00 - 3.30), 35.6 (95% CI: 33.90 - 37.30), and 3.8 (95% CI: 1.80 - 5.70) percent, respectively. The prevalence of refractive errors significantly varied across different age groups overall and by sex (P = 0.01). The proportion of refractive errors also significantly differed by education (P = < 0.001). The prevalence of against the rule, with the rule, and oblique astigmatism was 32.8 % (95% CI: 31.10 - 34.20), 42.1% (40.50 - 43.60), and 24.9% (23.10 - 26.60), respectively. The risk of astigmatism was significantly lower in men than in women (OR = 0.75; 95 % CI: 0.60 - 0.90). Based on multiple regression, the risk of myopia (OR = 2.07; 95 % CI: 1.60 - 2.60) and hyperopia (OR = 25.38; 95 % CI: 18.70 - 34.3) was higher in the age group 65 to 75 years compared to the younger group. Conclusions: The present study provided valuable information on the prevalence of refractive errors in the adult population in south-eastern Iran. The findings underscore the need for comprehensive eye care services, particularly for older individuals and those with lower education levels. Further prospective research is warranted to explore the factors contributing to refractive errors and to develop effective strategies for its prevention and management.

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Abobotulinum toxin A for periorbital facial rejuvenation: impact on ocular refractive parameters

Cited by 4 publications

References 11 publications

Treatment of periorbital wrinkles using thermo‐mechanical fractional injury therapy versus fractional non‐ablative 1565 nm laser: A comparative prospective, randomized, double‐arm, controlled study

Treatment of periorbital wrinkles using thermo‐mechanical fractional injury therapy versus fractional non‐ablative 1565 nm laser: A comparative prospective, randomized, double‐arm, controlled study

Evaluation of Mitomycin C Effect on Corneal Endothelial Cell Density After Photorefractive Keratectomy

Prevalence of Refractive Errors and Associated Factors in the Population of the Eye Cohort Study in Southeast Iran

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