Abrasion of Pro Seal® and Opal® Seal™ by professional tooth cleaning protocols: results from an <i>in vitro</i> study and a randomized controlled trial

Deurer, Nadine; Erber, Ralph; Orhan, Gül; Zingler, Sebastian; Lux, Christopher J.; Şen, Sinan

doi:10.1093/ejo/cjz096

Cited by 2 publications

(11 citation statements)

References 20 publications

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“…In a previous work using OCT, we showed surface sealants layer thickness reduction after professional tooth cleaning in vitro and in vivo in patients wearing fixed appliances [9]. The purpose of the present singlecenter randomized controlled trial was to evaluate surface sealant thickness and integrity during a 12-month follow-up in patients wearing fixed appliances using OCT.…”

Section: Introductionmentioning

confidence: 75%

“…To ensure a balance in sample size across groups, block randomization was used (four quadrants in each block). As reported previously, due to the different optical properties of the sealants used in this study which makes them easily identifiable, blinding of raters was not possible [9]. Thus, neither patients nor clinical practitioners and raters were blinded.…”

Section: Study Population Randomization and Blindingmentioning

confidence: 91%

“…The original study protocol, which included four study arms by combining two different orthodontic sealant materials and two different tooth cleaning procedures, was recently published [9]. Since the focus of the current report is the longitudinal observation of the abrasion behavior and integrity of the two included surface sealants, within this manuscript, the study will be presented and discussed as a 2-arm RCT.…”

Section: Methodsmentioning

confidence: 99%

“…PTC procedures were performed as previously described [9] by two dental hygienists with over 20 years of experience on the job. As suggested by Migliorati et al [11], PTC procedures were performed every 3 months, after the integration of the fixed appliance during the observation time of 12 months.…”

Section: Study Population Randomization and Blindingmentioning

confidence: 99%

“…Study outcomes: longitudinal assessment of sealant thickness and integrity using OCT imaging Using a modified ophthalmic OCT device (Spectralis®; Heidelberg Engineering GmbH), thickness and integrity of sealant materials were assessed longitudinally on the central incisors. Volume scan mode was chosen to perform stacks of cross-sectional OCT images which were perpendicular to the labial tooth surface, parallel oriented to the bracket slots and with a layer width of 99 μm as previously reported [8,9].…”

Section: Study Population Randomization and Blindingmentioning

confidence: 99%

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OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial

et al. 2020

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Objectives The aim of this single-center randomized controlled trial (NCT03753256) was to assess orthodontic surface sealant layer thickness and integrity in vivo during a 12-month follow-up by optical coherence tomography (OCT). Materials and methods Using a split-mouth design, quadrants of 20 patients treated with fixed orthodontic appliances were included. Quadrants were randomly assigned to the sealants Pro Seal® (PS) or Opal® Seal™ (OS). OCT scans were performed immediately after the application of the sealants and after 3, 6, 9, and 12 months. Sealant layer thicknesses and their integrity were determined at 5 regions of interest (ROIs) known for high risks of demineralization. Sealant integrity loss was determined using a self-developed scale. Results A total of 16 patients successfully completed the study. The studied sealants showed significant differences in initial layer thickness. Mean layer thickness was significantly lower for PS (67.8 μm, (95% CI, 56.1-79.5)) than for OS (110.7 μm, (95% CI, 97.3-124.1)). Layer thickness loss was significant after 3 months for PS and after 6 months for OS. Sealant integrity was compromised in more than 50% of the ROIs already after 3 months for both sealants. Conclusions Patients treated with fixed orthodontic surface sealants lost the integrity of the protective layer in more than 50% of cases after 3 months, and the layer thickness of the sealants was significantly reduced after 3-6 months. Clinical relevance The protective effect against demineralization lesions of orthodontic sealants in patients treated with fixed appliances appears to be limited in time. Further preventive measures should be investigated. Trial registration ClinicalTrials.gov (NCT 03753256

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Section: Introductionmentioning

confidence: 75%

Section: Study Population Randomization and Blindingmentioning

confidence: 91%

Section: Methodsmentioning

confidence: 99%

Section: Study Population Randomization and Blindingmentioning

confidence: 99%

Section: Study Population Randomization and Blindingmentioning

confidence: 99%

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OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial

et al. 2020

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Non-invasive three-dimensional thickness analysis of oral epithelium based on optical coherence tomography—development and diagnostic performance

Trebing

Şen

Rues

et al. 2021

Heliyon

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Evaluating structural changes in oral epithelium can assist with the diagnosis of cancerous lesions. Two-dimensional (2D) non-invasive optical coherence tomography (OCT) is an established technique for this purpose. The objective of this study was to develop and test the diagnostic accuracy of a three-dimensional (3D) evaluation method. Methods: The oral lip mucosa of 10 healthy volunteers was scanned using an 870-nm spectral-domain OCT device (SD-OCT) with enhanced depth imaging (EDI). Four raters semi-automatically segmented the epithelial layer twice. Thus, eighty 3D datasets were created and analyzed for epithelial thickness. To provide a reference standard for comparison, the raters took cross-sectional 2D measurements at representative sites. The correlation between the 2D and 3D measurements, as well as intra-and inter-rater reliability, were analyzed using intraclass correlation coefficients (ICC).Results: Mean epithelial thickness was 280 AE 64μm (range 178-500 μm) and 268 AE 49μm (range 163-425 μm) for the 2D and 3D analysis, respectively. The inter-modality correlation of the thickness values was good (ICC: 0.76 [0.626-0.846]), indicating that 3D analysis of epithelial thickness provides valid results. Intra-rater and interrater reliability were good (3D analysis) and excellent (2D analysis), suggesting high reproducibility. Conclusions: Diagnostic accuracy was high for the developed 3D analysis of oral epithelia using non-invasive, radiation-free OCT imaging. Clinical significance: This new 3D technique could potentially be used to improve time-efficiency and quality in the diagnosis of epithelial lesions compared with the 2D reference standard.

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Abrasion of Pro Seal® and Opal® Seal™ by professional tooth cleaning protocols: results from an in vitro study and a randomized controlled trial

Cited by 2 publications

References 20 publications

OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial

OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial

Non-invasive three-dimensional thickness analysis of oral epithelium based on optical coherence tomography—development and diagnostic performance

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