Gallium-68 (T 1/2 = 68 min, I β+ = 89%) is an important positron-emitting radionuclide for positron emission tomography and used in nuclear medicine for diagnosing tumours. This study gives a suitable reaction to produce 68 Ga. Gallium-68 excitation function via 68 Zn(p, n) 68 Ga, 68 Zn(d, 2n) 68 Ga, 70 Zn(p, 3n) 68 Ga and 65 Cu(α, n) 68 Ga reactions were calculated by ALICE-91 and TALYS-1.0 codes. The calculated excitation function of 68 Zn(p, n) 68 Ga reaction was compared with the reported measurement and evaluations. Requisite thickness of the targets was obtained by SRIM code for each reaction. The 68 Ga production yield was evaluated using excitation function and stopping power.