Absorption, Transport, Distribution in Tissues and Bioavailability

Canene‐Adams, Kirstie; Erdman, John W.

doi:10.1007/978-3-7643-7501-0_7

Cited by 42 publications

(58 citation statements)

References 141 publications

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“…Further details about the transport and distribution of carotenoids (Erdman Jr. et al, 1993, Reboul, 2013, Canene-Adams and Erdman Jr., 2009) as well as the numerous health benefits and rare adverse effects (Britton et al, 2009a) were reviewed previously.…”

Section: General Aspects Of Carotenoid Absorption and Distribution Inmentioning

confidence: 99%

Carotenoid Deposition in Plant And Animal Foods and Its Impact on Bioavailability

Schweiggert

Carle

2015

Critical Reviews in Food Science and Nutrition

103

126

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Over the past decades, an enormous body of literature dealing with the natural deposition of carotenoids in plant- and animal-based foods has accumulated. Prominent examples are the large solid-crystalline aggregates in carrots and tomatoes or the lipid-dissolved forms in dairy products and egg yolk. Latest research has identified lipid-dissolved forms in a rare number of plant foods, such as tangerine tomatoes and peach palm fruit (Bactris gasipaes Kunth). In addition, liquid-crystalline forms were assumed in so-called tubular chromoplasts of numerous fruits, e.g., in papaya, mango, and bell pepper. The bioavailability of carotenoids from fresh and processed foods strongly depends on their genuine deposition form, since their effective absorption to the human organism requires their liberation from the food matrix and subsequent solubilization into mixed micelles in the small intestine. Consequently, a broad overview about the natural array of carotenoid deposition forms should be helpful to better understand and modulate their bioavailability from foods. Furthermore, naturally highly bioavailable forms may provide biomimetic models for the improved formulation of carotenoids in food supplements. Therefore, this review paper presents scientific evidence from human intervention studies associating carotenoid deposition forms with their bioavailability, thus suggesting novel technological and dietary strategies for their enhanced absorption.

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Section: General Aspects Of Carotenoid Absorption and Distribution Inmentioning

confidence: 99%

Carotenoid Deposition in Plant And Animal Foods and Its Impact on Bioavailability

Schweiggert

Carle

2015

Critical Reviews in Food Science and Nutrition

103

126

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“…Transfer efficiency seems to be influenced by solubility as reflected in the micellarised localisation of different carotenoid types. Carotenes are embedded in the triacylglycerol-rich core of micelles, while xanthophylls with more hydroxyl or other functional groups are more polar (Matsuno et al, 1986;Tyssandier et al, 2003), and are expected to reside closer to the surface monolayer, together with proteins, phospholipids, and partially ionised fatty acids (Canene-Adams & Erdman, 2009). This suggests that xanthophylls are more readily incorporated into lipid-bile micelles (Garrett, Failla, & Sarama, 1999;Van Buggenhout et al, 2010), although this may vary amongst green vegetables containing membrane or protein-bound chloroplasts (Failla, Huo, & Thakkar, 2008).…”

Section: Accepted M Manuscriptmentioning

confidence: 99%

Mastication effects on carotenoid bioaccessibility from mango fruit tissue

Low

D'Arcy

Gidley

2015

Food Research International

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“…1 The most common carotenoids in the Western diet are alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein, and zeaxanthin. 2 After absorption in the intestine, carotenoids are transported through the bloodstream by lipoproteins to various target tissues, 3,4 including skin.…”

Section: 0 Introduction To Skin Carotenoids: Health Effectsmentioning

confidence: 99%

Resonance Raman spectroscopic evaluation of skin carotenoids as a biomarker of carotenoid status for human studies

Mayne

Cartmel

Scarmo

et al. 2013

Archives of Biochemistry and Biophysics

100

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Resonance Raman Spectroscopy (RRS) is a non-invasive method that has been developed to assess carotenoid status in human tissues including human skin in vivo. Skin carotenoid status has been suggested as a promising biomarker for human studies. This manuscript describes research done relevant to the development of this biomarker, including its reproducibility, validity, feasibility for use in field settings, and factors that affect the biomarker such as diet, smoking, and adiposity. Recent studies have evaluated the response of the biomarker to controlled carotenoid interventions, both supplement-based and dietary [e.g., provision of a high-carotenoid fruit and vegetable (F/V)-enriched diet], demonstrating consistent response to intervention. The totality of evidence supports the use of skin carotenoid status as an objective biomarker of F/V intake, although in the cross-sectional setting, diet explains only some of the variation in this biomarker. However, this limitation is also a strength in that skin carotenoids may effectively serve as an integrated biomarker of health, with higher status reflecting greater F/V intake, lack of smoking, and lack of adiposity. Thus, this biomarker holds promise as both a health biomarker and an objective indicator of F/V intake, supporting its further development and utilization for medical and public health purposes.

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Absorption, Transport, Distribution in Tissues and Bioavailability

Cited by 42 publications

References 141 publications

Carotenoid Deposition in Plant And Animal Foods and Its Impact on Bioavailability

Carotenoid Deposition in Plant And Animal Foods and Its Impact on Bioavailability

Mastication effects on carotenoid bioaccessibility from mango fruit tissue

Resonance Raman spectroscopic evaluation of skin carotenoids as a biomarker of carotenoid status for human studies

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