Abstract 10281: Predictors of Gastrointestinal Bleeding in Patients Undergoing Percutaneous Mitral Valve Repair- A Us National Inpatient Database Analysis

Abstract

Introduction: Data on outcomes and predictors of gastrointestinal (GI) bleeding in patients undergoing percutaneous mitral valve repair (PMVR) remains limited. Hypothesis: GI bleed is associated with worse outcomes in patients undergoing PMVR Methods: We utilized the national inpatient sample data from the year 2015 to 2018 to evaluate outcomes and predictors of GI bleed in patients undergoing PMVR. Results: A total of 21,505 weighted hospitalizations were included in the analysis. Of the patients who underwent PMVR, 285 (1.3%) developed GI bleed whereas 21220 (98.7%) did not have in-hospital GI bleed event. The mean age of patient with and without GI bleed was 77 and 76 years respectively (P<0.01). A logistic regression model was developed for adjusted comparison based on age, gender and baseline comorbidities. On adjusted comparison history of MI (OR 1.56, 95% CI 1.17-2.08), congestive heart failure (OR 1.79, 95% CI 1.18-2.73), African American race (OR 1.75, 95% CI 1.16-2.66) and history of weight loss (OR 2.71, 95% CI 1.97-3.74) were associated with significantly increased risk of gastrointestinal bleeding. Patients who developed GI bleed had significantly higher in-hospital mortality (8.8%) compared to non-GI bleeders (2.1%). Length of stay (16 vs. 4 days) and cost of hospitalization ($ 66118 vs. $49167) was significantly higher for GI bleeders undergong PMVR. Conclusions: In conclusion we report that GI bleed is associated with higher in-hospital mortality and resource utilization in patients undergoing PMVR.