Abstract PR441

Kim, Y. B.; Kim, H. J.; Ro, Young Jin; Ko, Wonwook; Lee, K. C.; Kim, H. S.; Yang, Hong Seuk

doi:10.1213/01.ane.0000492829.20005.77

Cited by 1 publication

(1 citation statement)

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“…However, ablative fractional erbium-doped yttrium aluminum garnet (Er-YAG) laser-assisted drug treatment may be superior to CO 2 fractional laser treatment because it may have fewer side effects (such as post-inflammatory hyperpigmentation), while they have a common therapeutic concept of ablative fractional resurfacing for drug delivery. 6 A combined use of fractional laser and other skin damage treatments such as microneedling therapy, radiofrequency waves were also proposed in order to achieve the best efficacy of treatment 2,7 , however, whether the application of topical AMSC metabolite product and the use of fractional erbium YAG laser can be combined in clinical use for facial rejuvenation had not been realized until recently.…”

Section: Introductionmentioning

confidence: 99%

The efficacy and safety of fractional erbium yag laser combined with topical amniotic membrane stem cell (AMSC) metabolite product for facial rejuvenation: A controlled, split-face study

Widianingsih¹,

Setyaningrum²,

Prakoeswa³

2019

Dermatol Reports

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Skin aging is a complex biological process, and it growing fast in number. Fractionated laser has been considered as the gold standard for skin rejuvenation. Stem cell-based therapy also becoming a promising new approach for treating this condition. To investigate the effect of fractional erbium laser and topical amniotic membrane stem cell (AMSC)-metabolite product (MP) on skin aging. A total of 9 female participants, were included in controlled split-face study. The participant’s face was randomly allocated to AMSC-MP or saline, immediately after fractional laser procedure. All participants received 3 sessions of treatment with 4-weeks intervals. An evaluation was done using pre- and post- treatment photographs and skin analyzer, Janus. Laser-assisted transdermal delivery drug using topical AMSC-MP give a better improvement on skin pore and spot UV compared with the control group. The wrinkle and skin tone showed different results maybe because of multifactorial factors influence. No serious adverse events were found. This study suggest that fractional erbium YAG laser treatment combined with topical AMSC–MP is effective and safe for facial rejuvenation in Asian patients.

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Section: Introductionmentioning

confidence: 99%