Acanthomatous ameloblastoma of mandible crossing the midline: A rare case report

Abstract

Ameloblastoma is the most common aggressive benign odontogenic tumor of the jaws. Ameloblastoma is a benign epithelial odontogenic tumor that typically arises in the mandible or maxilla or, rarely, in the immediate adjacent soft tissues. A clinical, radiographic and histopathological report is presented of a case of acanthomatous ameloblastoma in relation to molar in the left mandible of a 30-year-old healthy male. The histopathological examination of the removed specimen revealed the histopathological pattern of an acanthomatous ameloblastoma. The radiographic appearance of the lesion showed the presence of multilocular radiolucencies, which were crossing the midline, which is rarely found in ameloblastoma. Due to its rarity and lack of data, we take this opportunity to present a world first case of acanthomatous ameloblastoma which was crossing the midline.

Mixed-Pattern Ameloblastoma of the Anterior Mandible: A Rare Histopathological Presentation at an Infrequent Location

“…The acanthomatous subtype has been reported to occur mostly in the posterior mandible of older patients, with a peak incidence during the seventh decade of life (mean age: 61.3 ± 1.2 years) [5]. To our knowledge, only a few cases of acanthomatous ameloblastomas affecting the anterior mandible have been reported in the literature, either in young [6,7] or relatively elderly patients [8]. Acanthomatous metaplasia has been observed to correlate with chronic irritation, attributed to calculus and oral sepsis.…”

“…Various histological subtypes of ameloblastomas have been described, including the most prevalent, follicular (64.9%), followed by the plexiform (13%), desmoplastic (5.2%), and acanthomatous (3.9%) variants [5]. Moreover, there are only a few reports presenting ameloblastomas of the rare acanthomatous subtype that were located at the anterior region of the mandible and crossed its midline [6][7][8].…”