Acaricidal activity of the essential oil from Senecio cannabifolius and its constituents eucalyptol and camphor on engorged females and larvae of Rhipicephalus microplus (Acari: Ixodidae)

Yang, Peipei; Jia, Mengmeng; Zhu, Liang

doi:10.1007/s10493-021-00590-x

Cited by 11 publications

(8 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies have correlated monoterpenes and sesquiterpenes with the biocidal action of EOs from different plants. Although the mechanism of action is not fully understood, it is already described in the literature, several monoterpenes are neurotoxic because they inhibit the enzyme acetylcholinesterase, and have the ability to interfere with the metabolic functions of arthropods (Jankowska et al, 2018;Medeiros et al, 2019;Yang et al, 2021). For example, 1,8-cineol (eucalyptol) extracted from Lippia alba has remarkable insecticidal activity (Lima et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Activity of essential oils from leaves, flower buds and stems of Tetradenia riparia on Rhipicephalus (Boophilus) microplus larvae

Cella

Rahal

Silva

et al. 2023

Rev. Bras. Parasitol. Vet.

View full text Add to dashboard Cite

Around the world, the main problems of livestock are caused by ectoparasites, however, commercial acaracide are toxic to the environment and detrimental to One Health. Therefore, research has increasingly focused on development of natural products as alternatives for tick control. The purpose of this study was to evaluate the larvicidal effect on Rhipicephalus (Boophilus) microplus, through use of essential oils (EOs) extracted from the leaves, flower buds and stems of Tetradenia riparia. The chemical composition of these EOs was determined through gas chromatography coupled to mass spectrometry (GC-MS). They were tested on larvae at concentrations of 100.000 to 40 µg/mL, using the larval packet test and under semi-natural conditions. The main class of compounds in the chemical composition was sesquiterpenes (both oxygenates and hydrocarbons), whereas the predominant compounds in the leaves, flower buds and stems were 14-hydroxy-9-epi-caryophyllene, T-cadinol and 6-7-dehydroroyleanone, respectively. The leaves proved to be the most effective, with highest larvicidal activity (LC99.9 = 83.53 µg/mL). When tested under semi-natural conditions, the oils obtained efficiency above 98% in all compound tests. The results indicated that these EOs were effective against R. (B.) microplus larvae in vitro and ex-situ, proving that this plant has bioactive molecules with significant larvicidal activity.

show abstract

Section: Discussionmentioning

confidence: 99%

“…For example, 1,8-cineol (eucalyptol) extracted from Lippia alba has remarkable insecticidal activity (Lima et al, 2021). Moreover, eucalyptol extracted from the EOs of Senecio cannabifolius (Yang et al, 2021), Melinis minutiflora (Prates et al, 1998) and Eucalyptus globulus (Chagas et al, 2002) was found to be able to kill 100% of R. (B.)…”

Section: Discussionmentioning

confidence: 99%

Activity of essential oils from leaves, flower buds and stems of Tetradenia riparia on Rhipicephalus (Boophilus) microplus larvae

Cella

Rahal

Silva

et al. 2023

Rev. Bras. Parasitol. Vet.

View full text Add to dashboard Cite

show abstract

“…Therefore, it is particularly important to nd plantderived natural products with insecticidal activity. Eucalyptol is an effective component of secondary metabolites in many plants, including Senecio cannabifolius (Wu et al 2006;Yang et al 2021), Cinnamum cassia, and Laurus nobilis (Wang et al 2019). In addition, many studies also have reported that eucalyptol has insecticidal and repellent effects on insects including Aedes aegypti (Diptera: Culicidae), Musca domestica, and Chrysomya megacephala (Klocke et al 1987;Sukontason et al 2004).…”

Section: Introductionmentioning

confidence: 99%

An epsilon class glutathione S-transferase gene contributes to the phytochemical susceptibility of Tribolium castaneum

Gao

Zhou

et al. 2023

Preprint

View full text Add to dashboard Cite

Evidence is accumulating that insect epsilon class glutathione S-transferases (GSTes) play an important role in the resistance of xenobiotics such as insecticide. A Tribolium castaneum epsilon class GST gene, TcGSTe17, could be significantly induced following exposure to plant derivative eucalyptol. However, whether TcGSTe17 involved in resistance to eucalyptol is still unclear. In this study, the TcGSTe17 was cloned from the T. castaneum genome, which exhibited the characteristic structural domain of epsilon class GSTs. In addition, molecular docking analysis showed that TcGSTe17 possibly could interact with eucalyptol. The expression profiling of stage showed that TcGSTe17 expressed at all development stages, of which highly expressed at late larvae. The expression profiling of tissue showed that TcGSTe17 highly expressed in gut of larvae and fat body of adults, respectively, and exhibited gender-different expression patterns as well. In addition, the transcripts of TcGSTe17 were significantly increased following exposure to eucalyptol, and RNAi heightened the susceptibility of beetles to eucalyptol. Overall, these results suggest that TcGSTe17 is required for the susceptibility of T. castaneum to eucalyptol. This study will contribute to the development of molecular targets, and provide scientific basis for developing eucalyptol as an insecticide.

show abstract

“…Eucalyptol has gastroprotective (Rocha Caldas et al, 2015) and anti‐inflammatory (Juergens et al, 2003) activity. In a study of insecticidal activity, high concentrations of eucalyptol reduced the activity of glutathione S‐transferase (GST), β‐esterase, and p–Nitrophenyl acetate in Rhipicephalus microplus (Acari: Ixodidae) (Yang et al, 2021). In addition, eucalyptol has insecticidal and repellent effects on Aedes aegypti (Diptera: Culicidae), Musca domestica (Diptera: Muscidae), and Chrysomya megacephala (Diptera: Calliphoridae) (Klocke et al, 1987; Sukontason et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

“…Sesquiterpenes and pyrrolizidine alkaloids in secondary metabolites extracted from Senecio cannabifolius (Campanulales: Asteraceae) can be used to treat viral influenza, icteric hepatitis, and stomach ailments. The main components of EOs extracted from S. cannabifolius are camphor and eucalyptol (Wu et al, 2006; Yang et al, 2021). In addition, eucalyptol accounts for 23.71% of Cinnamum cassia oil (Laurales: Lauraceae) and 54.38% of Laurus nobilis oil (Ranunculales: Lauraceae) (Wang et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Contact toxicity of eucalyptol and RNA sequencing of Tribolium castaneum after exposure to eucalyptol

Gao

Huo

Guo

et al. 2023

Entomological Research

View full text Add to dashboard Cite

Eucalyptol, the main active component of Artemisia vulgaris (A. vulgaris) essential oil, can reduce the activity of Tribolium castaneum (T. castaneum) metabolic detoxification enzymes. However, the molecular mechanism underlying the toxic effect of eucalyptol on T. castaneum is still unclear. Here, results showed that the eucalyptol caused time‐dependent increase in larval mortality. Further, 1669 differential expressed genes (DEGs) expressed between the control group and the experimental group were detected via RNA sequencing, of which 504 were upregulated and 1165 were downregulated. The validity of the RNA‐Seq results was verified by qRT‐PCR. Further, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases were used to analyze the DEGs, focusing on immune system process, response to stimulus, and developmental process in the GO analysis and on the excretory system and the metabolism of terpenoids and polyketides in the KEGG analysis. The results showed that the upregulation of Apolipoprotein D and the downregulation of V‐type proton ATPase subunits, farnesol dehydrogenase, receptor tyrosine‐protein phosphatase ε and α may affect the growth and metabolism of T. castaneum larvae. In the KEGG pathway analysis, we focused on the role of certain metabolic detoxification enzymes in the regulation of eucalyptol‐stimulated T. castaneum. Among them, the expression of metabolic detoxification enzymes OBP10, CYP4C1, CYP6BS1, CYP4g15, CYP301A1, CYP49A1, UGTs2C1, UGTs2B2, UGTs2B16, and Est FE4 was downregulated. The expression of OBPC01, OBPC09, OBPC12, OBPC02, OBPC11, CYP345B1, CYP346B1, Est E4, Est 6, and GST1 increased significantly. These metabolic detoxification enzymes were involved in the detoxification of eucalyptol by T. castaneum, and their downregulation or upregulation may indirectly affect insect survival and death. Our results provide an overview of transcriptomic changes in eucalyptol‐stimulated T. castaneum and enriches the candidate transcripts that can be exploited for pest control initiatives.

show abstract

Acaricidal activity of the essential oil from Senecio cannabifolius and its constituents eucalyptol and camphor on engorged females and larvae of Rhipicephalus microplus (Acari: Ixodidae)

Cited by 11 publications

References 38 publications

Activity of essential oils from leaves, flower buds and stems of Tetradenia riparia on Rhipicephalus (Boophilus) microplus larvae

Activity of essential oils from leaves, flower buds and stems of Tetradenia riparia on Rhipicephalus (Boophilus) microplus larvae

An epsilon class glutathione S-transferase gene contributes to the phytochemical susceptibility of Tribolium castaneum

Contact toxicity of eucalyptol and RNA sequencing of Tribolium castaneum after exposure to eucalyptol

Contact Info

Product

Resources

About