Accelerated (9 mW/cm2) Corneal Collagen Crosslinking for Keratoconus—A 1-Year Follow-up

Elbaz, Uri; Shen, Carl; Lichtinger, Alejandro; Zauberman, Noa Avni; Goldich, Yakov; Chan, Clara C.; Slomovic, Allan R.; Rootman, David S.

doi:10.1097/ico.0000000000000299

Cited by 29 publications

(38 citation statements)

References 6 publications

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“…Recently, Hashemi et al compared the 6-month results of accelerated and standard collagen CXL treatments for progressive keratoconus and determined that the mean changes in uncorrected and corrected visual acuities, as well as the mean decreases in the maximum K and mean K values, did not differ statistically significantly between the groups (13) . Elbaz et al retrospectively studied the efficacy of accelerated CXL in 16 keratoconus-affected eyes and reported the effectiveness of this procedure for the stabilization of topographic parameters, including Ksteep, Kflat, average K, corneal astigmatism, and maximal curvature reading at the corneal apex, after 12 months of follow-up (14) . Mita et al also evaluated the effectiveness of accelerated CXL in 39 eyes and reported significantly improved UCVA and Kmax values at 6 months after treatment (15) .…”

Section: Discussionmentioning

confidence: 99%

Factors affecting visual acuity after accelerated crosslinking in patients with progressive keratoconus

Kirgiz¹,

Atalay²,

Çabuk³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Purpose: The present study aimed to report the outcomes of patients with progressive keratoconus who were treated via accelerated crosslinking (CXL) 6 months earlier and to determine the factors that promoted improved visual acuity after treatment. Methods: This retrospective study included 35 eyes of 34 patients with progres sive keratoconus who underwent CXL. Topographical measurements were obtained preoperatively and in the first, third, and sixth months postoperatively using a rotating Scheimpflug camera. The uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), flat keratometry (K) value (K1), steep K value (K2), average K value (avgK), topographic cylindrical value (Cyl), apical keratoscopy front (AKf ), apical keratoscopy back (AKb), symmetry index front (SIf ), symmetry index back (SIb), and thinnest point of the cornea (ThkMin) were recorded. Results: At the 6-month follow-up, the mean UCVA and BCVA values were improved, and the K values remained stable. Statistically significant decreases in AKf (p=0.04) and the thinnest point of the cornea (p=0.001) and a statistically significant increase in AKb (p=0.01) were observed. A correlation analysis revealed that the preoperative BCVA, UCVA, K1, K2, avgK, AKf, and AKb values significantly affected visual acuity at the 6-month follow-up. Conclusions: Accelerated CXL is an effective treatment for the prevention or even reversal of keratoconus progression. The preoperative K values and apexes of the anterior and posterior cornea were found to affect visual acuity at 6 months after accelerated CXL. Both AKb steepening and AKf flattening appear to be important factors in the stabilization of keratometric values and improvement of visual outcomes.

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Section: Discussionmentioning

confidence: 99%

Factors affecting visual acuity after accelerated crosslinking in patients with progressive keratoconus

Kirgiz¹,

Atalay²,

Çabuk³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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“…12 Preliminary non-comparative clinical studies using different accelerated CXL settings with illumination intensities up to 30 mW/cm 2 for 3 min demonstrated safety and favourable efficacy of accelerated CXL on keratoconus. [13][14][15][16][17][18][19] However, some studies were limited by the short follow-up duration or small number of cases. Gatziofas et al only included seven eyes with six months follow-up, and Kymionis et al only reported the three months outcome for 10 eyes.…”

Section: Introductionmentioning

confidence: 99%

Conventional versus accelerated corneal collagen cross‐linking in the treatment of keratoconus

Chan

Cheng

2015

Clinical Exper Ophthalmology

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“…23 Similarly, variable results (0.06-0.8 D) were obtained in adult groups following accelerated corneal CXL. 15,25 Another finding of our study was that the number of patients whose progression did not halt was higher in the pediatric group (5/41) compared to the adult group (2/47). This is probably due to the fact that keratoconus is more aggressive at pediatric ages.…”

Section: Discussionmentioning

confidence: 48%

Accelerated Corneal Crosslinking Results with Respect to Age Groups

Koç¹,

Uzel²,

Koban³

et al. 2018

Turkiye Klinikleri J Ophthalmol

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Accelerated (9 mW/cm2) Corneal Collagen Crosslinking for Keratoconus—A 1-Year Follow-up

Cited by 29 publications

References 6 publications

Factors affecting visual acuity after accelerated crosslinking in patients with progressive keratoconus

Factors affecting visual acuity after accelerated crosslinking in patients with progressive keratoconus

Conventional versus accelerated corneal collagen cross‐linking in the treatment of keratoconus

Accelerated Corneal Crosslinking Results with Respect to Age Groups

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