Accelerated Amination of Baylis–Hillman Acetates Under Ultrasound Irradiation

Synthesis of Imidazopyridines from the Morita–Baylis–Hillman Acetates of Nitroalkenes and Convenient Access to Alpidem and Zolpidem

“…From another perspective, the Morita–Baylis–Hillman (MBH) reaction has emerged in recent decades as one of the most sought after reactions for the synthesis of various multifunctional scaffolds . The MBH acetates of electron-deficient alkenes have been subjected to substitution, often S N 2′, by numerous nucleophiles including amines under uncatalyzed, organocatalyzed and metal-catalyzed conditions. − However, to our knowledge, synthesis of imidazopyridines from the MBH adducts of electron-deficient alkenes, including nitroalkenes, remains unreported …”