Processing large volumes of data has presented a challenging issue, particularly in data-redundant systems. As one of the most recognized models, the conditional random fields (CRF) model has been widely applied in biomedical named entity recognition (Bio-NER). Due to the internally sequential feature, performance improvement of the CRF model is nontrivial, which requires new parallelized solutions. By combining and parallelizing the limited-memory Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) and Viterbi algorithms, we propose a parallel CRF algorithm called MRCRF (MapReduce CRF) in this paper, which contains two parallel sub-algorithms to handle two time-consuming steps of the CRF model. The MRLB (MapReduce L-BFGS) algorithm leverages the MapReduce framework to enhance the capability of estimating parameters. Furthermore, the MRVtb (MapReduce Viterbi) algorithm infers the most likely state sequence by extending the Viterbi algorithm with another MapReduce job. Experimental results show that the MRCRF algorithm outperforms other competing methods by exhibiting significant performance improvement in terms of time efficiency as well as preserving a guaranteed level of correctness.Index Terms-Biomedical named entity recognition, conditional random fields, MapReduce, parallel algorithm.