Access to the Superstrong Segregation Regime with Nonionic ABC Copolymers

New micellar morphologies from amphiphilic block copolymers: disks, toroids and bicontinuous micelles

“…Disk-like (or oblate spherical) micelles, whilst remaining relatively rare, have been observed to form from a number of ABC-type amphiphilic copolymers with non-ionic 49,50 as well as ionic hydrophilic blocks.…”

Synthesis and Micellar Characterization of CBABC Type PLGA-PEO-PPO-PEO-PLGA Pentablock Copolymers

“…8,9 Microphase separations of solid block copolymers have been also widely reported such as cubic, hexagonal, lamella, and gyroid phases, which is attributed to its molecular weight, volume fractions of each block, and Flory-Huggins interaction parameter (χ). [10][11][12] In these processes, the free energy is known to be balanced between the forces of minimizing interfacial area and the constituent blocks to be random coils both in bulk and solution. [10][11][12] Pluronic poly(ethylene oxide)-b-poly(propylene oxide)-bpoly(ethylene oxide) (PEO-PPO-PEO) triblock copolymers are well-known polymeric surfactant, which have been used as a compatibilizer in polymer blends and a nano-carrier for biomedical applications.…”

“…[10][11][12] In these processes, the free energy is known to be balanced between the forces of minimizing interfacial area and the constituent blocks to be random coils both in bulk and solution. [10][11][12] Pluronic poly(ethylene oxide)-b-poly(propylene oxide)-bpoly(ethylene oxide) (PEO-PPO-PEO) triblock copolymers are well-known polymeric surfactant, which have been used as a compatibilizer in polymer blends and a nano-carrier for biomedical applications. [13][14][15] Especially, Pluronic micelles are one of good candidates for various biomedical areas such as drug delivery and biosensor due to its biocompatibility, temperature sensitivity, and good solubility in aqueous solution.…”

Synthesis of ABC and CABAC Triphilic Block Copolymers by ATRP Combined with ‘Click’ Chemistry

“…[19] However, there are limited studies that have reported on such triphilic systems. [19][20][21][22][23] This communication describes a simple route to synthesize triphilic block copolymers. Converting excess dihydroxy-terminated poly(propylene oxide) (HO-PPO-OH) ATRP using poly(propylene oxide) monofunctional macroinitiator was carried out with solketal methacrylate (SMA) and the non-reactive PPO having two N 3 terminal groups was removed by dissolution in an excess of n-hexane.…”