Acculturation and chronic kidney disease in the Hispanic community health study/study of Latinos (HCHS/SOL)

Lora, Claudia M.; Ricardo, Ana C.; Chen, Jinsong; Cai, Jianwen; Flessner, Michael F.; Moncrieft, Ashley E.; Peralta, Carmen A.; Raij, Leopoldo; Rosas, Sylvia E.; Talavera, Gregory A.; Daviglus, Martha L.; Lash, James P.

doi:10.1016/j.pmedr.2018.04.001

Cited by 15 publications

(10 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In combination with ROS and MAP, the number of Latinx participants across RADC cohort studies is approaching a total of 500 participants. Latinxs in RADC cohort studies reported low levels of ac-culturation, similar to those found in the HCHS/SOL cohort [97]. Latinxs also reported higher levels of neuroticism and depressive symptoms compared with non-Latinx blacks and whites.…”

Section: Discussionsupporting

confidence: 67%

Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer’s Disease Center

et al. 2020

View full text Add to dashboard Cite

The Rush Alzheimer’s Disease Center (RADC) conducts 5 harmonized prospective clinical-pathologic cohort studies of aging – with 1 study, the Latino Core, focused exclusively on Latinxs, 2 studies consisting of mostly non-Latinx whites, and 2 studies of mostly non-Latinx blacks. This paper contextualizes the Latino Core within the other 4 harmonized RADC cohort studies. The overall aim of the paper is to provide information from the RADC, so that researchers can learn from our participants and procedures to better advance the science of Alzheimer’s disease and related dementias in Latinxs. We describe an annual clinical evaluation that assesses risk factors for Alzheimer’s dementia among older adults without known dementia at enrollment. As all RADC cohort studies offer brain donation as a part of research participation, we discuss our approach to brain donation and subsequent participant decision-making among older Latinxs. We also summarize baseline characteristics of older Latinxs across the 5 RADC cohort studies in relation to the baseline characteristics of non-Latinx blacks and non-Latinx whites. Finally, we outline challenges and considerations as well as potential next steps in cognitive aging research with older Latinxs.

show abstract

Section: Discussionsupporting

confidence: 67%

Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer’s Disease Center

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Next we sought to understand the relationship of GMB with acculturation, or adaptation of features of the US environment, which varied across birthplace and relocation age groups (Table 2) [17–19]. English language preference was associated with lower Prevotella to Bacteroides ratio and lower fungal Shannon diversity (Fig.…”

Section: Resultsmentioning

confidence: 99%

Gut microbiome composition in the Hispanic Community Health Study/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity

et al. 2019

Self Cite

View full text Add to dashboard Cite

BackgroundHispanics living in the USA may have unrecognized potential birthplace and lifestyle influences on the gut microbiome. We report a cross-sectional analysis of 1674 participants from four centers of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), aged 18 to 74 years old at recruitment.ResultsAmplicon sequencing of 16S rRNA gene V4 and fungal ITS1 fragments from self-collected stool samples indicate that the host microbiome is determined by sociodemographic and migration-related variables. Those who relocate from Latin America to the USA at an early age have reductions in Prevotella to Bacteroides ratios that persist across the life course. Shannon index of alpha diversity in fungi and bacteria is low in those who relocate to the USA in early life. In contrast, those who relocate to the USA during adulthood, over 45 years old, have high bacterial and fungal diversity and high Prevotella to Bacteroides ratios, compared to USA-born and childhood arrivals. Low bacterial diversity is associated in turn with obesity. Contrasting with prior studies, our study of the Latino population shows increasing Prevotella to Bacteroides ratio with greater obesity. Taxa within Acidaminococcus, Megasphaera, Ruminococcaceae, Coriobacteriaceae, Clostridiales, Christensenellaceae, YS2 (Cyanobacteria), and Victivallaceae are significantly associated with both obesity and earlier exposure to the USA, while Oscillospira and Anaerotruncus show paradoxical associations with both obesity and late-life introduction to the USA.ConclusionsOur analysis of the gut microbiome of Latinos demonstrates unique features that might be responsible for health disparities affecting Hispanics living in the USA.

show abstract

“…In the HCHS/SOL, lower language acculturation was associated with CKD among older adults (>65 years of age); however, among those with CKD, acculturation measures were not associated with hypertension or diabetes control. 18…”

Section: Social Determinants Of Ckdmentioning

confidence: 99%

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Tsao¹,

Aday²,

Almarzooq³

et al. 2022

Circulation

3,830

2,336

View full text Add to dashboard Cite

Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2022 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population and an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, and the global burden of cardiovascular disease and healthy life expectancy. Results: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

show abstract

Acculturation and chronic kidney disease in the Hispanic community health study/study of Latinos (HCHS/SOL)

Cited by 15 publications

References 32 publications

Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer’s Disease Center

Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer’s Disease Center

Gut microbiome composition in the Hispanic Community Health Study/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Contact Info

Product

Resources

About