Accuracy of contrast-enhanced ultrasound compared with conventional ultrasound in acute pancreatitis: Diagnosis and complication monitoring

Abstract

Contrast-enhanced ultrasound (CEUS) has been used for diagnosing acute pancreatitis (AP), particularly severe acute pancreatitis (SAP). However, the diagnostic difference between CEUS and conventional ultrasonography (CUS) for AP and SAP has not been reported. The aim of the present study was to investigate the diagnostic accuracy of CUS and CEUS for AP. A total of 196 patients clinically diagnosed with AP were selected. All patients underwent CUS, CEUS and contrast-enhanced computed tomography (CECT) within 72 h. CECT was considered the gold standard. Pancreatic size, peripancreatic fluid collection (PPFC) and splenic vessel complications were the variables observed by CUS and CEUS. The differences in the variables among the three methods were analyzed using the χ2 test and statistical analysis software. Significant differences in pancreatic size, PPFC and splenic vessel complications in AP were observed between CEUS and CUS (P<0.05). χ2 test results indicated that CEUS significantly differed from CUS in terms of having a higher diagnostic accuracy for AP and SAP (P<0.05). The results indicate that CEUS is a reliable method for the diagnosis and monitoring of AP and SAP, and may be substituted for CECT.

Pancreatic Evaluation in Dogs using Different Ultrasonographic Techniques – Preliminary Results

“…Studies performed by Rademacher et al [4] and Lim et al [9] also presented an increase in the time of entrance and peak enhancement in dogs with pancreatitis. Results of CEUS technique were not effective in differentiation of altered tissues in most cases, however, it was possible to detect microvascularization, contrary to the study performed by Cai et al [24] which demonstrated that in cases of acute pancreatitis, this method allows successful identifi cation of changes in comparison to B mode ultrasonography, with an accuracy of 78.0% (103/132) and 47.7% (63/132), respectively. Vanderperren et al [25] also verifi ed a differentiation of exocrine and endocrine pancreatic tumors using CEUS: adenocarcinomas were presented hypovascular and insulinomas were hypervascular.…”

Multifactorial Scores and Biomarkers of Prognosis of Acute Pancreatitis: Applications to Research and Practice

“…Golea et al [74] concluded that contrast-enhanced ultrasound (CEUS) is usefulness in the quantification of the necrosis area in AP. Cai et al [76] conducted a study to evaluate the accuracy of conventional US and CEUS in patients with AP, concluding that CEUS is a reliable method for the diagnosis and prognosis of AP, and it may serve as a substitute for CECT. Skouras et al [77], by studying the characteristics of lung ultrasonography and its role in the diagnosis of respiratory dysfunction, proposed that this exam may be an adjuvant in the assessment of the severity of pancreatitis.…”

Effectiveness of contrast-enhanced ultrasound for the diagnosis of acute pancreatitis: A systematic review and meta-analysis

“…Out of 27 clinical studies, seven fulfilled the inclusion criteria and were included in the meta-analysis [9,[16][17][18][19][20][21]. There was a total of 421 AP cases.…”