Accuracy of mammography and sonomammography and its correlation with histopathology in the detection of breast cancer

Abstract

Background: Mammography (MMG) plays a pivotal role in the early diagnosis of breast cancer (BC). However, it is sometimes difficult to use it to diagnose palpable breast lesions among young patients. Ultrasound can be used as an adjunct in differentiating cystic and solid masses. Studies evaluating the combination of MMG and sonomammography (SMG) as an adjunct to detect Breast cancer, are quite scarce in the literature. This study aimed to assess the accuracy of MMG and to comprehend the role of ultrasound as an adjunct to MMG for finding breast lesions.Methods: Women attending the outpatient department (OPD) with complaints of breast lump, or those undergoing MMG screening were included. All patients then subsequently underwent MMG, SMG and biopsy. MMG and SMG findings were then correlated with the histopathology results.Results: Irregular shape and calcifications (MMG) and hypoechoic pattern (SMG) were found to be significant features differentiating malignant from benign lesions. Calcifications in benign tumors were observed 5.05 times less frequently than in malignant tumors. MMG combined with SMG had a sensitivity of 90.4%, specificity of 82.4%, positive and negative predictive value of 95% and 67% respectively, along with an accuracy of 88.9% in differentiating benign from malignant masses.Conclusions: SMG used as an adjunct to MMG is a reliable modality, especially in detecting lesions that are not picked up on MMG, including intraductal papilloma and duct ectasia.

Comparing the Diagnostic Value of Sonomammography and MRI with Diffusion Techniques in Detection and Characterization of Lesions in Mammographically Dense Breast

“…There were 88 individuals with thick breasts in this research. This is consistent with Yamakanamardi and Hiremath (17) , who said that there were 90 patients in all of the instances. The patients were between the ages of 40 and 65.…”

“…The patients were between the ages of 40 and 65. Between the ages of 40 and 50, where there were the most instances (85.3% of all cases), This is consistent with the research by Yamakanamardi and Hiremath (17) , which found that the majority of patients with malignant breast lesions were between the ages of 41 and 50.…”

“…In our investigation, 41% of the total numbers of malignant breast lesions were worrisome breast calcifications. This is consistent with Yamakanamardi and Hiremath (17) , who found that 60% of the malignant tumors overall were suspicious breast calcifications. The commonality in age group may be the root of this agreement.…”

“…The commonality in age group may be the root of this agreement. Whereas most of the patients in Yamakanamardi and Hiremath's (17) study were between the ages of 41 and 60, in our study 85.3% of the patients were under the age of 40.…”

Diagnostic Accuracy of MR Mammography in Comparison with Digital Mammography and Sonomammography

“…Sonomammography (diagnostic or targeted ultrasound) is a high-resolution ultrasound of the breast and it plays an important role in the evaluation of breast cancer [5]. It is effective in differentiating solid and fluid-containing masses.…”