Accuracy of MR Imaging in endometrial cancer: our experience

Sampath, S.; Nema, Devendra; Agarwal, Raju; Lele, Prasad

doi:10.18203/2320-1770.ijrcog20171441

Cited by 4 publications

(7 citation statements)

References 10 publications

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“…Manfredi R et al 15 stated that there was significant agreement between MR imaging and surgico-pathologic findings in assessment of myometrial invasion. Similar results were also reported by Shrivastava et al 13 and Sampath et al 14 The overall Sensitivity of MRI for staging of EC in this study was 91.84% and accuracy was 90%. Thus, the present study showed concordance in MRI & FIGO Staging for EC and similar results were observed in the study conducted by Shrivastava et al 13 Our study was also comparable to the before mentioned studies in terms of tumour grade differentiation.…”

Section: Discussionsupporting

confidence: 92%

“…Thus, the present study showed concordance in MRI & FIGO Staging for EC and similar results were observed in the study conducted by Shrivastava et al 13 Our study was also comparable to the before mentioned studies in terms of tumour grade differentiation. 14,15 Overall, similar to our study findings, Shrivastava et al 13 mentioned that the information provided by MRI can define prognosis, help planning the surgical approach and identify those patients requiring neoadjuvant chemotherapy or radiation therapy.…”

Section: Discussionsupporting

confidence: 88%

“…In our study, MRI had an accuracy of 82% in estimating the tumour size. A study by Sampath et al 14 found the accuracy of MRI for estimation of tumour size 72% with a sensitivity of 90%. For detecting myometrial infiltration, our study showed that MRI had an accuracy of 90% with Sensitivity of 97.3% and Specificity of 69.23%.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Role of MRI in pre-operative staging of endometrial cancer: A diagnostic accuracy study

Kharde¹,

Swapnil²,

Phulambrikar³

et al. 2022

IJOGR

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Endometrial cancer (EC) is a commonly occurring cancer among post-menopausal women. Pre-treatment imaging of the extent of disease can influence the decisions in the management of EC. MRI with its diffusion weighted (DW) images can help in better depiction of the primary tumour, its local extension and extrauterine spread to the peritoneum and lymph nodes. This study was conducted to know the role of MRI for pre-operative staging of endometrial cancer and as a guide for pelvic lymph nodal dissection.It was a descriptive cross-sectional study conducted at a tertiary care hospital patients diagnosed with primary endometrial adenocarcinoma on biopsy. Patients with advanced disease requiring chemotherapy prior to surgery were excluded. Fifty consecutive patients were subjected to MRI Pelvis with abdominal screening in the week preceding definitive surgery, Findings from imaging were compared with final histopathology for concurrence on tumour size, depth of myometrial invasion, presence of adnexal, nodal and cervical stromal involvement.Majority of the patients in this study were post-menopausal women. Sensitivity of MRI for staging of Endometrial Carcinoma in this study was 91.84% and Accuracy was 90%. When compared to HPE for lymph node positivity, MRI had sensitivity of 100%, specificity of 97.87%, PPV of 75%, NPV of 100% and accuracy of 98%.Pre-operative MRI in the week prior to the planned surgery can help in accurately staging the endometrial carcinoma in terms of myometrial infiltration, cervical stromal infiltration as well as pelvic lymph nodal involvement.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 88%

See 1 more Smart Citation

Role of MRI in pre-operative staging of endometrial cancer: A diagnostic accuracy study

Kharde¹,

Swapnil²,

Phulambrikar³

et al. 2022

IJOGR

View full text Add to dashboard Cite

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“…Our patient's MRI results ( Fig. 2 ) showed a mass with irregular edges, which is iso-to-hyperintense in signal intensity on T2WI [ [37] , [38] ]. After contrast injection, the inner myometrial layer or JZ is enhanced uniformly during the earlier dynamic phase as a continuous band or a “sub-endometrial stripe” [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

“…EC can be depicted with DWI as areas of increased signal intensity relative to the surrounding hypointense myometrium [ 67 ]; thus, DWI can aid in the diagnosis of MI . DWI had slightly higher diagnostic accuracy (94.3% vs 88.6%), a slightly greater specificity (95.5% vs 86.4%), and the same level of sensitivity (92.3%) as DCE-MRI in assessing the depth of MI [ 37 ]. The positive predictive values (PPV) and NPV of DWI were 52.4% and 92.3%, superior to DCE-MRI, which had corresponding PPV and NPV values of 40.9% and 84.0%, respectively [16] .…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging pitfalls in determining myometrial invasion in stage I endometrial cancer: A case report and literature review

Winarto

Habiburrahman²,

Siregar³

et al. 2022

Radiology Case Reports

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Endometrial Cancer Staging: Is There Value in ADC?

Moreira

Ribeiro

Aringhieri

et al. 2023

JPM

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Purpose: To assess the ability of apparent diffusion coefficient (ADC) measurements in predicting the histological grade of endometrial cancer. A secondary goal was to assess the agreement between MRI and surgical staging as an accurate measurement. Methods: Patients with endometrial cancers diagnosed between 2018–2020 and having received both MRI and surgical staging were retrospectively enrolled. Patients were characterized according to histology, tumor size, FIGO stage (MRI and surgical stage), and functional MRI parameters (DCE and DWI/ADC). Statistical analysis was performed to determine if an association could be identified between ADC variables and histology grade. Secondarily, we assessed the degree of agreement between the MRI and surgical stages according to the FIGO classification. Results: The cohort included 45 women with endometrial cancer. Quantitative analysis of ADC variables did not find a statistically significant association with histological tumor grades. DCE showed higher sensitivity than DWI/ADC in the assessment of myometrial invasion (85.00% versus 65.00%) with the same specificity (80.00%). A good agreement between MRI and histopathology for the FIGO stage was found (kappa of 0.72, p < 0.01). Differences in staging between MRI and surgery were detected in eight cases, which could not be justified by the interval between MRI and surgery. Conclusions. ADC values were not useful for predicting endometrial cancer grade, despite the good agreement between MRI interpretation and histopathology of endometrial cancer staging at our center.

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Accuracy of MR Imaging in endometrial cancer: our experience

Cited by 4 publications

References 10 publications

Role of MRI in pre-operative staging of endometrial cancer: A diagnostic accuracy study

Role of MRI in pre-operative staging of endometrial cancer: A diagnostic accuracy study

Magnetic resonance imaging pitfalls in determining myometrial invasion in stage I endometrial cancer: A case report and literature review

Endometrial Cancer Staging: Is There Value in ADC?

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