Accuracy of peritoneal fluid measurements by transvaginal ultrasonography

Verguts, Jasper; Timmerman, Dirk; Bourne, Tom; Lewi, Paul; Koninckx, Philippe

doi:10.1002/uog.7632

Cited by 7 publications

(4 citation statements)

References 11 publications

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“…Intraperitoneal volumes were calculated from the sonographic measurements of height, width and depth of the remaining fluid reservoir using an experimental formula (30). Moreover, the reliability of this method has recently been corroborated by other groups (31).…”

Section: Discussionsupporting

confidence: 53%

Comparison of 2 Different Barrier Solutions (icodextrin 4% vs. dextran 70) used as Adhesion-prevention Agents after Microsurgical Adnexal Operations

Deus

Kropf

Kleinstein

2014

Journal of Endometriosis and Pelvic Pain Disorders

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In this prospective randomized clinical trial, 2 different barrier solutions (icodextrin 4% vs. dextran 70) were compared with regard to their antiadhesive properties, their tolerance and their persistence in situ. To this end, 45 patients suffering from infertility due to adnexal adhesions with indication for microsurgical adhesiolysis were randomized to 2 treatment groups. In advance of abdominal closure, patients were randomized to receive either 1,000 mL of icodextrin 4% solution (n = 23) or 300 mL dextran 70 instillation (n = 22). Serial transvaginal ultrasonographic scans were conducted on days 1, 3, 5 and 7 after surgery to measure the remaining volumes of each barrier solution. Seven days after initial surgery, a second-look laparoscopy was performed; remaining fluids were aspirated and measured and adhesions were rescored (final adhesion score). Differences between treatment groups were not significant (p = 0.775). With regard to their tolerance, the advantages of the icodextrin 4% solution became obvious, as edema of vulva and abdomen occurred more frequently after dextran 70 instillation. In conclusion, microsurgical adhesiolysis and application of icodextrin 4% solution or dextran 70 as adhesion-prevention agent resulted in reduction of incidence, extent and severity of adhesions. Both solutions were well tolerated.

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Section: Discussionsupporting

confidence: 53%

Comparison of 2 Different Barrier Solutions (icodextrin 4% vs. dextran 70) used as Adhesion-prevention Agents after Microsurgical Adnexal Operations

Deus

Kropf

Kleinstein

2014

Journal of Endometriosis and Pelvic Pain Disorders

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“…Higher volumes of lavage fluid should be avoided since peptides and secreted factors withstand long-term storage and future analysis better when concentrated (Raymond Anchan, M.D., personal communication). The optimal position to collect either peritoneal or lavage fluid is in a 30° reverse Trendelenburg position (39) .…”

Section: Resultsmentioning

confidence: 99%

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research

Adamson

Allaire²,

Anchan³

et al. 2014

Fertility and Sterility

167

158

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ObjectiveTo standardize the recording of surgical phenotypic information on endometriosis and related sample collections obtained at laparoscopy, allowing large-scale collaborative research into the condition.DesignAn international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries.SettingTwo workshops were conducted in 2013, bringing together 54 clinical, academic, and industry leaders in endometriosis research and management worldwide.Patient(s)None.Intervention(s)A postsurgical scoring sheet containing general and gynecological patient and procedural information, extent of disease, the location and type of endometriotic lesion, and any other findings was developed during several rounds of review. Comments and any systematic surgical data collection tools used in the reviewers' centers were incorporated.Main Outcome Measure(s)The development of a standard recommended (SSF) and minimum required (MSF) form to collect data on the surgical phenotype of endometriosis.Result(s)SSF and MSF include detailed descriptions of lesions, modes of procedures and sample collection, comorbidities, and potential residual disease at the end of surgery, along with previously published instruments such as the revised American Society for Reproductive Medicine and Endometriosis Fertility Index classification tools for comparison and validation.Conclusion(s)This is the first multicenter, international collaboration between academic centers and industry addressing standardization of phenotypic data collection for a specific disease. The Endometriosis Phenome and Biobanking Harmonisation Project SSF and MSF are essential tools to increase our understanding of the pathogenesis of endometriosis by allowing large-scale collaborative research into the condition.

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“…As described before, 21 women were placed in a 30°anti-Trendelenburg position and, after 1 minute, the three dimensions (length, height and depth) of the pocket of fluid was measured 3 times by ultrasonography using an Esaote Technos system with a 6.5-MHz transvaginal probe (Esaote, Genoa, Italy). Using these measurements, the peritoneal volume was calculated.…”

Section: Measurement Of Peritoneal Volumementioning

confidence: 99%

Clearance Rates of Ringer's Lactate and Adept and the Effect of Full Conditioning: A Randomized Controlled Trial

VergutsJasper

CoronaRoberta

TimmermanDirk

et al. 2015

Journal of Gynecologic Surgery

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Background: Instillation of crystalloid flotation agents, such as Ringer's lactate has been suggested for preventing adhesion formation after abdominal surgery, but the efficacy of this approach remains controversial. Objective: The aim of this pilot study was to evaluate the resorption rates of Ringer's lactate and icodextrin 4% following a pneumoperitoneum with CO 2 and humidification (control) in comparison with a pneumoperitoneum with 86%CO 2 + 10%N 2 O + 4%O 2 together with cooling and humidification (full conditioning). Materials and Methods: Twenty women undergoing laparoscopic hysterectomy were prospectively randomized to have during surgery with a control or a full-conditioned pneumoperitoneum as well as the instillation of 1000 mL of Ringer's lactate or icodextrin 4% at the end of surgery. Fluid volumes remaining after 24, 48, and 72 hours were measured by ultrasound testing. Results: The peritoneal volumes of Ringer's lactate and icodextrin 4% both decreased exponentially over time. Following a pneumoperitoneum with CO 2 , the resorption rate of Ringer's lactate was faster than for icodextrin 4%. After 24, 48, and 72 hours 11.7 -1.0% versus 38.2 -9.5% ( p = 0.009), 5.3 -0.6% versus 14.9 -4.8% (NS), and 4.2 -0.7% versus 12.1 -4% ( p = 0.03), respectively of the initial 1 L remained. Conditioning decreased the resorption rate of Ringer's lactate and after 24, 48, and 72 hours 25.2 -3.4, 13.2 -1.3 and 6.0 -0.5% remained ( p = 0.03, 0.009, and NS versus the control group), respectively Conditioning did not affect the resorption rate of icodextrin. Conclusions: The absorption of both Ringer's lactate and of icodextrin 4% from the peritoneal cavity was fast and exponential in this pilot study. In the control group, the resorption rate of icodextrin 4% was slightly slower than that of Ringer's lactate. After conditioning, the resorption rate of Ringer's was slower and became comparable to that of icodextrin 4%. ( J GYNECOL SURG 31:139)

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Accuracy of peritoneal fluid measurements by transvaginal ultrasonography

Abstract: Objective

Cited by 7 publications

References 11 publications

Comparison of 2 Different Barrier Solutions (icodextrin 4% vs. dextran 70) used as Adhesion-prevention Agents after Microsurgical Adnexal Operations

Comparison of 2 Different Barrier Solutions (icodextrin 4% vs. dextran 70) used as Adhesion-prevention Agents after Microsurgical Adnexal Operations

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research

Clearance Rates of Ringer's Lactate and Adept and the Effect of Full Conditioning: A Randomized Controlled Trial

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