Accuracy of the Holladay 2 intraocular lens formula for pediatric eyes in the absence of preoperative refraction

Abstract

The Holladay 2 formula had the least prediction error and absolute prediction error even in the absence of preoperative refraction.

Comparison of IOL power calculation formulae for pediatric eyes

“…One study 11 has reported that age, AL, and K values did not influence predictive accuracy, except for the Holladay and Hoffer Q formulae that were influenced by AL. On the other hand, several authors 5,10,12 reported that a shorter AL had a significant bearing on the predictive accuracy of the IOL calculation formula.…”

“…In adult eyes, it is known that even with state-of-the-art techniques and equipment, a surgeon who fails to optimize his constants could have less accurate outcomes than someone using older equipment who does optimize. 22 Trivedi et al 10 (Poster presentation at the annual meeting of the American Academy of Ophthalmology, 2011) reported that personalizing the lens constant improves the PE and APE in pediatric eyes. Whereas we found that the mean PE improved significantly after personalizing the lens constants.…”

“…[4][5][6][7][8][9] Further, several authors have compared the accuracy of different IOL formulae designed for adult eyes in predicting early postoperative refractive error in eyes of infants and young children. 7,[9][10][11][12] However, there is no consensus as to which formula provides the best prediction of early postoperative refraction, particularly in the extremely small eye. In adult eyes, formulae that may have an advantage in terms of accuracy based on AL are: ALo22 mm: Hoffer Q, Holladay 2; AL 22-26 mm: Holladay I, Hoffer Q, SRK/T; AL426 mm: SRK/T, Holladay 2.…”

“…12 In pediatric eyes, however, results are inconsistent. [4][5][6][7][8][10][11][12] Further, most published studies in the literature are retrospective. [4][5][6][7][8]10,11 Optimizing or personalizing the lens constant has been recommended by authors of several formulae to improve their accuracy and predictability.…”

“…[4][5][6][7][8][10][11][12] Further, most published studies in the literature are retrospective. [4][5][6][7][8]10,11 Optimizing or personalizing the lens constant has been recommended by authors of several formulae to improve their accuracy and predictability. [13][14][15][16] Personalizing the lens constant can be used to make global adjustments for a variety of practice-specific variables (eg, surgical technique, variations in AL and K measurements, and so on).…”