Accuracy of Ultrasonography With Color Doppler in Ovarian Tumor

Medeiros, Lídia Rosi; Rosa, Daniela Dornelles; Rosa, Maria Inês da; Bozzetti, Mary Clarisse

doi:10.1111/igc.0b013e31819c1369

Cited by 39 publications

(16 citation statements)

References 28 publications

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“…However, there is no consensus as to which Doppler parameters and cutoff values are the most predictive of malignancy because of the overlap in blood flow parameters between benign and malignant lesions. In addition, conventional Doppler US has inherent limitations, such as inferior sensitivity to slow flow and deeply located blood vessels [5]–[7]. 3-D power Doppler US provides a new method to evaluate the tumor vascularity.…”

Section: Introductionmentioning

confidence: 99%

The Contribution of Qualitative CEUS to the Determination of Malignancy in Adnexal Masses, Indeterminate on Conventional US – A Multicenter Study

et al. 2014

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The aim of this study is to evaluate the efficacy of qualitative analysis of contrast-enhanced ultrasound (CEUS) in discrimination of adnexal masses which were undetermined by conventional ultrasound (US). A total of 120 patients underwent transabdominal CEUS. The initial enhancement time and intensity compared with the uterine myometrium, contrast agent distribution patterns and dynamic changes of enhancement were assessed. The sensitivity (Sen), specificity (Spe), positive predictive value (PPV), negative predictive value (NPV), accuracy (ACC) and Youden’s index were calculated for contrast variables. The gold standard was the histological diagnosis. There were 48 malignant tumors and 72 benign tumors. The enhancement features of malignant masses were different from benign ones. Earlier or simultaneous enhancement with inhomogeneous enhancement yielded the highest capability in differential diagnosis, and Sen, Spe, PPV, NPV, ACC, Youden’s index was 89.6%, 97.2%, 93.2%, 95.6%, 93.3%, and 0.88, respectively. The qualitative evaluation of CEUS is useful in the differential diagnosis of adnexal masses where conventional US is indeterminate.

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Section: Introductionmentioning

confidence: 99%

The Contribution of Qualitative CEUS to the Determination of Malignancy in Adnexal Masses, Indeterminate on Conventional US – A Multicenter Study

et al. 2014

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“…The corresponding overall sensitivity and specificity of RMI alone were 68% (95% CI, 63–72%) and 93% (95% CI, 91–94%). There are other second‐line tests with proven efficacy that are relatively easy to perform, for example color Doppler30, but no Doppler data were available in this study. However, future research should evaluate the value of a sequential approach with RMI and HistoScanning that contains Doppler information and compare this with the ‘simple‐rules’ strategy.…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic ventral hernia repair (Br J Surg 2012; 99: 1319–1321)

Aellen

2013

British Journal of Surgery

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A bit of a stretch! A series of stable Lewis base adducts of a dimeric magnesium(I) complex has been prepared and shown to possess exceptionally long MgMg bonds. Theoretical studies on model compounds suggest the elongations of these bonds are low‐energy processes. The structures of the magnesium(I) adducts are compared with those of related magnesium(II) hydride complexes (see picture; Mg pink, N blue, O red, H green).

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“…Malignant tumors show a reliance on new vessel formation. Low‐impedance intratumoral flow is usually observed in cases of primary ovarian cancer, and the resistive index is commonly less than 0.4 in these cases 18 . However, a PubMed search showed no earlier studies dealing with the discrimination of low‐ and high‐grade serous carcinoma by conventional sonography.…”

Section: Discussionmentioning

confidence: 99%