Accuracy of WASCA Aberrometer Refraction Compared to Manifest Refraction and Cycloplegic Refraction in Hyperopia Measurement

Abstract

To explore the agreement between the wavefront supported custom ablation (WASCA) aberrometer and manifest refraction (MR) and cycloplegic refraction (CR) in hyperopia testing. Methods: Ninety eyes of 90 hyperopic patients (spherical equivalent ≥ +0.5 D) were evaluated; MR, CR, and WASCA refraction (WR) were performed consecutively. Analysis pupil size was 6.0 mm in WASCA measurement using the Seidel method. The conventional notation was transferred into vector components for analysis, i.e., spherical equivalent (M) and two cross-cylinders at axis 0°(J 0) and axis 45°(J 45). Bland-Altman plots were used to test the agreement between the two measurements. Results: The mean Ms obtained with MR and CR were 3.23 ± 1.74 D and 4.04 ± 2.04 D, respectively (P < 0.001), and the correlation was high (r = 0.90, P < 0.001). The WR was highly correlated with MR and CR in terms of M (r = 0.89, 0.87), but not significantly correlated in J 0 and J 45. The total dioptric power vector error was 0.18 ± 1.00 D between WR and MR and −0.64 ± 1.03 D between WR and CR. The limits of agreement of all vector components were beyond ± 1.0 D. With hyperopia level increase, WR tended to overestimate MR (P = 0.04), whereas WR always underestimated CR. Conclusions: WASCA could act as a reference of subjective refraction in hyperopia measurement, the exchangeability is not fully applicable. Translational Relevance: WASCA can provide an alternative for objective refraction in hyperopia measurement.

The optics of the human eye at 8.6 µm resolution

“…Most likely, it will take years of clinical studies to learn how to interpret this new information, associate it with different pathologies or conditions, and determine whether it has a real clinical application or is just a curiosity. The applications of ocular aberrometry are ubiquitous: they include refractive surgery (i.e., LASIK) 28 , the diagnosis and monitoring of diseases 29 , myopia control 30 , intraocular lenses 31 , light-adjustable intraocular lenses 32 , objective refraction 33 , intraoperative aberrometry 34 , and vision science 35 . Additionally, combining a wavefront sensor with a compensating element, such as a liquid crystal spatial light modulator, has dramatically improved in vivo observations of the human retina 36 .…”

The optics of the human eye at 8.6 µm lateral resolution

“…Most likely, it will take years of clinical studies to learn how to interpret this new information, associate it with different pathologies or conditions, and determine whether it has a real clinical application or is just a curiosity. The applications of ocular aberrometry are ubiquitous: they include refractive surgery (i.e., LASIK) [28], the diagnosis and monitoring of diseases [29], myopia control [30], intraocular lenses [31], light- adjustable intraocular lenses [32], objective refraction [33], intraoperative aberrometry [34], and vision science [35]. Additionally, combining a wavefront sensor with a compensating element, such as a liquid crystal spatial light modulator, has dramatically improved in vivo observations of the human retina [36].…”

Grading Sphero-Cylinder Spectacle Similarity

“…7 There are technical methods to compare two spectacle refractions; Bland Altman plot analysis of vector transformed astigmatism 8 is a valid, but complicated method for spectacle comparison. 9 Time spent viewing through different fixed lenses in cages by nonhuman primates is a low tech method to compare objective and subjective refractions. 10 Donated spectacles are made available for lay people to distribute to needy people in remote areas.…”