The urban heat island (UHI) is one of the essential phenomena of the modern urban climate. In recent years, urbanization in China has gradually accelerated, and the heat island effect has also intensified as the urban impervious surface area and the number of buildings is increasing. Urban building density (UBD) is one of the main factors affecting UHI, but there is little discussion on the relationship between the two. This paper takes Hefei as the research area, combines UBD data estimated by Luojia1-01 night-time light (NTL) imagery as the research object with land surface temperature (LST) data obtained from Landsat8 images, and carries out spatial correlation analysis on 0.5 × 0.5 km to 2 × 2 km resolution for them, so as to explore the relationship between UBD and UHI. The results show the following: (1) Luojia1-01 data have a good ability to estimate UBD and have fewer errors when compared with the actual UBD data; (2) At the four spatial scales, UBD and LST present a significant positive correlation that increases with the enlargement of the spatial scale; and (3) Moreover, the fitting effect of the Geographically Weighted Regression (GWR) model is better than that of the ordinary least squares (OLS) regression model. Appl. Sci. 2019, 9, 5224 2 of 20 absorbing heat faster and the specific heat capacity being smaller gives rise to limited heat release. In this way, the average LST in the area gradually increases with the spatial distribution of the UHI area to become more continuous and concentrated, forming a high-temperature area centered on artificial buildings in the city [1,9,10]. However, our comprehensive literature research found that past studies focused on the analysis of seasonal, daily, and annual variations of the UHI, which revealed the temporal and spatial variation of the UHI, the distribution characteristics of the horizontal and vertical directions, etc., while there has been less quantitative analysis of the single factors of UHIs, especially discussion of the ubiquitous relationship between impervious surfaces and UHI in the city.As an integral part of the urban impervious surface percentage, the urban building density (UBD) (percentage of built area) can directly reflect the degree of intensification and land-use efficiency in cities to some extent [11]. It is also an essential comprehensive social indicator that can function as an urban planning layout measure [12,13], resource utilization efficiency measure [14,15], and assessment of the urban ecological environment and livability [16][17][18][19]. Some researchers have pointed out that UBD is a crucial indicator to reduce the UHI effect [20] and proved a positive correlation between UBD and LST or UHI [21][22][23]. Additionally, researchers have tried to use a variety of urban design factors to study the relationships of UHIs, including UBD information. For example, Yang studied the summer heat island intensity of three high-rise residential districts in Shanghai, based on the three indices of building layout, density, and greeni...