Accurate Noninvasive Estimation of Left Ventricular End-Diastolic Pressure: Comparison with Catheterization

Neumann, Alex; Soble, Jeffrey S.; Anagnos, Peter C.; Kagzi, M.; Parrillo, Joseph E.

doi:10.1016/s0894-7317(98)70070-7

Cited by 9 publications

(2 citation statements)

References 23 publications

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“…Non-invaziv olarak SVDSB tahmin etmede en önemli tetkik ekokardiyografi dir. Ekokardiyografi de bakılan parametrelerin SVDSB tahmin etmedeki yeri bir çok çalışmada araştırılmıştır (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28). Yapılan bir çok çalışma ve ortaya konan formüllere rağmen özellikle SVEF korunmuş hastalarda dopler parametrelerinin SVEDB öngörmedeki güvenirlilikleri belirsizdir (3,5).…”

Section: Discussionunclassified

Value of Mitral A-Wave Acceleration Time on Estimation of Left Ventricular End-Diastolic Pressure

Akıllı¹,

Erer²,

Kayrak³

et al. 2015

Akd Med J

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Bu çalışmada sol ventrikül ejeksiyon fraksiyonunun korunduğu hastalarda (ejeksiyon fraksiyonu >%50), mitral A dalga yükselme zamanının, sol ventrikül diyastol sonu basıncını öngörmedeki yerinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Mayıs 2012 ile Ekim 2013 tarihleri arasında koroner anjiyografi yapılmasına karar verilen 121 hasta çalışmaya dahil edildi. Ekokardiyografi kayıtları alındıktan sonra, ölçümlerden habersiz başka bir araştırmacı tarafından sol kalp kateterizasyonu ile sol ventrikül diyastol sonu basıncı ölçüldü. Basınç değerlerine göre hastalar üç gruba ayrıldı. Sol ventrikül diyastol sonu basıncı 0 ile 10 mmHg arası olanlar grup 1, 11 ile 15 mmHg arasında olanlar grup 2, 16 mmHg ve üzeri olanlar ise grup 3'e dahil edildi. Demografi k özellikler, vital bulgular ve ekokardiyografi k parametreler gruplar arasında karşılaştırıldı. Bulgular: Çalışmamıza dahil edilen 121 hastadan 60 (%49,5) tanesi grup 1'e, 30 (%24,7) tanesi grup 2 ye, 31 (%25,6) tanesi grup 3 içerisine alındı. Gruplar arası yapılan analizde yaş, cinsiyet, vücut kitle indeksi, komorbit durumlar ve vital bulgular arasında anlamlı bir fark izlenmedi. Gruplar arasında mitral A dalga yükselme zamanında anlamlı bir fark izlenmedi. (Sırasıyla, 79,3±19,6 cm/sn, 83,9±12,5 cm/sn, 80,2±20,1 cm/sn p=0,51). Sonuç: Tüm bu bulgulara rağmen net veriler için daha fazla hasta katılımının olduğu çalışmalara ihtiyaç olduğu açıktır.

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Section: Discussionunclassified

Value of Mitral A-Wave Acceleration Time on Estimation of Left Ventricular End-Diastolic Pressure

Akıllı¹,

Erer²,

Kayrak³

et al. 2015

Akd Med J

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“…Left ventricular end-diastolic pressure (LVEDP) was estimated using the method described by Neumann et al (25). Briefly, the time of aortic valve opening was determined by using the leading edge of the aortic opening click on continuous-wave Doppler recording.…”

Section: M-mode 2-d and Doppler Echocardiographymentioning

confidence: 99%

Left Ventricular Diastolic Filling Characteristics Are Not Impaired but Systolic Performance Was Augmented in the Early Hours of Experimental Endotoxemia in Humans

Mathru

Pollard

et al. 2006

Shock

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This study was performed to determine whether endotoxemia causes diastolic cardiac dysfunction. Eleven healthy volunteers, 30 +/- 6 years of age, underwent comprehensive transthoracic echocardiographic assessment including two-dimensional, M-mode transmitral and tissue Doppler of systolic and diastolic function at baseline and at 3 and 5 h after intravenous administration of purified Escherichia coli endotoxin (4 ng/kg). Data were analyzed by analysis of variance; P values of less than 0.05 were considered significant. Endotoxin administration resulted in a hyperdynamic state characterized by decreased mean arterial pressure and significant increase in cardiac index. This was accompanied by increases in several load-dependent systolic performance indices (3 and 5 h). Robust increases in peak systolic blood pressure/end-systolic volume index, one of the relatively load-independent contractility parameter, were also observed at 3 h after endotoxin administration. Transmitral peak early velocity (E), which represents early filling, significantly increased at 3 h after infusion. Late diastolic velocity (A), which represents atrial contraction, significantly increased at 3 and 5 h after infusion. The E/A ratio indicative of delayed relaxation significantly decreased due to increases in A (transmitral) and A (tissue Doppler) at 3 and 5 h after infusion. As expected, endotoxin infusion resulted in a hyperdynamic state associated with increases in systolic function indices including endocardial systolic velocities. The observed decreases in E/A (transmitral) and E/A (tissue Doppler) ratio were primarily due to increases in A and A. Moreover, isovolumic relaxation time and time constant for left ventricular relaxation, a load-independent parameter for ventricular relaxation, remained unchanged at 3 and 5 h after endotoxin infusion. Therefore, our findings are more likely due to enhanced atrial contractility resulting from increased sympathetic activity in response to reduction in left ventricular afterload and not due to altered diastolic filling characteristics.

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Inadequate RAAS suppression is associated with excessive left ventricular mass and systo-diastolic dysfunction

Gregori¹,

Marra²,

Pignatelli³

et al. 2013

Clin Res Cardiol

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Accurate Noninvasive Estimation of Left Ventricular End-Diastolic Pressure: Comparison with Catheterization

Cited by 9 publications

References 23 publications

Value of Mitral A-Wave Acceleration Time on Estimation of Left Ventricular End-Diastolic Pressure

Value of Mitral A-Wave Acceleration Time on Estimation of Left Ventricular End-Diastolic Pressure

Left Ventricular Diastolic Filling Characteristics Are Not Impaired but Systolic Performance Was Augmented in the Early Hours of Experimental Endotoxemia in Humans

Inadequate RAAS suppression is associated with excessive left ventricular mass and systo-diastolic dysfunction

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