Acetaminophen and Febrile Seizure Recurrences During the Same Fever Episode

Murata, Shinichi; Okasora, Keisuke; Tanabe, Takuya; Ogino, Mieko; Yamazaki, Satoshi; Oba, Chizu; Syabana, Kohsuke; Nomura, Shouhei; Shirasu, Akihiko; Inoue, Kazuo; Kashiwagi, Masayuki; Tamai, Hiroshi

doi:10.1542/peds.2018-1009

Cited by 41 publications

(26 citation statements)

References 19 publications

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“…Interestingly, one trial found that antipyretics are ineffective in lowering the temperature at all during febrile episodes that are associated with febrile seizure [ 138 ]. However, a recent study concluded that rectal paracetamol administration significantly decreased the likelihood of recurrent febrile seizures during the same fever episode [ 140 ].…”

Section: Discussionmentioning

confidence: 99%

Symptomatic fever management in children: A systematic review of national and international guidelines

et al. 2021

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Introduction Divergent attitudes towards fever have led to a high level of inconsistency in approaches to its management. In an attempt to overcome this, clinical practice guidelines (CPGs) for the symptomatic management of fever in children have been produced by several healthcare organizations. To date, a comprehensive assessment of the evidence level of the recommendations made in these CPGs has not been carried out. Methods Searches were conducted on Pubmed, google scholar, pediatric society websites and guideline databases to locate CPGs from each country (with date coverage from January 1995 to September 2020). Rather than assessing overall guideline quality, the level of evidence for each recommendation was evaluated according to criteria of the Oxford Centre for Evidence-Based Medicine (OCEBM). A GRADE assessment was undertaken to assess the body of evidence related to a single question: the threshold for initiating antipyresis. Methods and results are reported according to the PRISMA statement. Results 74 guidelines were retrieved. Recommendations for antipyretic threshold, type and dose; ambient temperature; dress/covering; activity; fluids; nutrition; proctoclysis; external applications; complementary/herbal recommendations; media; and age-related treatment differences all varied widely. OCEBM evidence levels for most recommendations were low (Level 3–4) or indeterminable. The GRADE assessment revealed a very low level of evidence for a threshold for antipyresis. Conclusion There is no recommendation on which all guidelines agree, and many are inconsistent with the evidence–this is true even for recent guidelines. The threshold question is of fundamental importance and has not yet been answered. Guidelines for the most frequent intervention (antipyresis) remain problematic.

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Section: Discussionmentioning

confidence: 99%

Symptomatic fever management in children: A systematic review of national and international guidelines

et al. 2021

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“…The study concluded that use of paracetamol combined with tepid sponging was more effective in bringing down the temperature than using paracetamol alone. 7 A prospective study conducted to questionnaire-based study to evaluate the knowledge, attitude and practice of mothers of under-five children suffering with febrile convulsion at the Mofid children hospital. Sample consisted of 126 mothers of children with febrile convulsion.…”

Section: Literature Reviewmentioning

confidence: 99%

A Study to Assess the Effectiveness of Video Assisted Teaching Programme on Knowledge Regarding Seizure Among Mothers of Under Five Children in Selected Community Area, Uttar Pradesh

Verma

Minu

2021

Int J Res Rev

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Background: Children under five years of age are more prone to develop infection, as their immune system is immature. The study aimed to assess the level of knowledge regarding seizure disorder among mothers of under five children, to evaluate the effectiveness of video assisted teaching program regarding seizure disorder among mothers of under five children and to find out the association between the pretest knowledge with their selected demographic variables of selected community area Lucknow. Conceptual model used for the study was Rosentock’s modified health belief model Objective: To assess the pretest level of knowledge regarding seizure among mothers of under five children and assess the effectiveness of the video assisted teaching program regarding seizure among mothers of under five children and find out the association between the pretest knowledge with their selected demographic variables. Materials and Method: The research approach was evaluative, the research design was pre-experimental, a one group pre-and posttest design was used for the study. A sample was 30 mothers with children aged under five were selected through convenient sampling method on knowledge regarding seizure. It was assessed by structured questionnaire, where during the pretest the mothers of children aged under five were attended the video-assisted teaching regarding seizure. Posttest data were collected after 1 week of implementation of video-assisted teaching. Results: The data were analyzed by using descriptive and inferential statics. The result revealed that after the intervention the mean and standard deviation of post-test knowledge was 28.8 and 2.51 being compare to pre-test 11.4 and 3.15.It indicate that there was a significant improvement in the level of knowledge of participants. The calculated t value (20.30) on analyses of the data was found to be significant at p value 0.05. Conclusion: The video-assisted teaching was effective and improved the knowledge regarding seizure among mothers of under five year children. Keywords: Assess, Effectiveness, Video assisted teaching, Knowledge, Seizure, Mother of under five children.

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“…The cumulative incidence of FS is estimated to be 2-4 % in the United States and 8-10 % in Japan [2,3]. The risk of recurrence during the same febrile illness has been reported as around 15 % [4,5], and recurrence usually occurs within 24 h [6,7]. Prophylactic diazepam was previously widely administered to children with FS according to the clinical practice guideline for FS in Japan [8].…”

Section: Introductionmentioning

confidence: 99%

Change in the strategy for prophylactic diazepam use for febrile seizures and the impact on seizure recurrence within 24 h

Inoue

Adachi

Kawakami

et al. 2020

Seizure

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To investigate the association between reduced prophylactic diazepam usage and short-term recurrence of febrile seizures (FSs) after the FS practice guideline was updated in Japan. Method: In this single-center, retrospective study, children (6-60 months of age) with FS who were transported to our center by ambulance from January 2011 through December 2018 were included. Rectal administration of diazepam (0.3-0.5 mg/kg) after the first seizure and seizure recurrence within 24 h were compared between 2011-2015 (pre-guideline revision) and 2016-2018 (post-guideline revision).

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Acetaminophen and Febrile Seizure Recurrences During the Same Fever Episode

Cited by 41 publications

References 19 publications

Symptomatic fever management in children: A systematic review of national and international guidelines

Symptomatic fever management in children: A systematic review of national and international guidelines

A Study to Assess the Effectiveness of Video Assisted Teaching Programme on Knowledge Regarding Seizure Among Mothers of Under Five Children in Selected Community Area, Uttar Pradesh

Change in the strategy for prophylactic diazepam use for febrile seizures and the impact on seizure recurrence within 24 h

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