Background
Cardiovascular disease is the leading cause of increased mortality for adolescents with advanced kidney disease. The quality of preventive cardiovascular care may impact long-term outcomes for these patients.
Methods
We reviewed records of 196 consecutive adolescents from 8 centers with pre-dialysis chronic kidney disease, on dialysis, or with a kidney transplant who transferred to adult-focused providers. We compared cardiovascular risk assessment and therapy within and across centers. Predictors of care were assessed using multilevel models.
Results
Overall, 58% (range: 44%–86%, p=0.08 for variance) of five recommended cardiovascular risk assessments were documented. Recommended therapy for six modifiable cardiovascular risk-factors was documented 57% (26%–76%, p=0.09) of the time. Thirty-percent of patients (n=59) were reported to go through formal transition which was independently associated with a 21% increase in composite cardiovascular risk assessment (p<0.001). Transfer after 2006 and kidney transplant status were also associated with increased cardiovascular risk assessment (p<0.01 and p=0.045, respectively).
Conclusions
Adolescents with kidney disease receive sub-optimal preventive cardiovascular care, which may contribute to their high risk of future cardiovascular mortality. Great opportunity exists to improve outcomes for children with kidney disease by improving reliability of preventive care that may include formal transition programs.