Acid folic and pregnancy: A mandatory supplementation

Valentin, M.; Mazeau, Perrine Coste; Zérah, Michel; Ceccaldi, P F; Benachi, Alexandra; Luton, Dominique

doi:10.1016/j.ando.2017.10.001

Cited by 33 publications

(24 citation statements)

References 11 publications

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“…These studies demonstrate that supplements do not substitute a healthy balanced diet high in fruits and vegetables, although for some patients, supplements are essential to combat a lack of nutrient. Examples of this include calcium supplementation in patients taking steroids [ 243 ]; folic acid supplementation for women planning to have a baby [ 244 ]; vitamin D supplementation in those at risk of low vitamin D levels including children under 5, adults over 65, pregnant or breastfeeding women, or those with sun sensitivities, among others [ 245 ].…”

Section: Microbes and Inflammation In Cancer: Means Of Treatment Amentioning

confidence: 99%

The Complex Interplay between Chronic Inflammation, the Microbiome, and Cancer: Understanding Disease Progression and What We Can Do to Prevent It

Armstrong

Bording-Jorgensen

Dijk

et al. 2018

Cancers

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Cancer is a multifaceted condition, in which a senescent cell begins dividing in an irregular manner due to various factors such as DNA damage, growth factors and inflammation. Inflammation is not typically discussed as carcinogenic; however, a significant percentage of cancers arise from chronic microbial infections and damage brought on by chronic inflammation. A hallmark cancer-inducing microbe is Helicobacter pylori and its causation of peptic ulcers and potentially gastric cancer. This review discusses the recent developments in understanding microbes in health and disease and their potential role in the progression of cancer. To date, microbes can be linked to almost every cancer, including colon, pancreatic, gastric, and even prostate. We discuss the known mechanisms by which these microbes can induce cancer growth and development and how inflammatory cells may contribute to cancer progression. We also discuss new treatments that target the chronic inflammatory conditions and their associated cancers, and the impact microbes have on treatment success. Finally, we examine common dietary misconceptions in relation to microbes and cancer and how to avoid getting caught up in the misinterpretation and over inflation of the results.

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Section: Microbes and Inflammation In Cancer: Means Of Treatment Amentioning

confidence: 99%

The Complex Interplay between Chronic Inflammation, the Microbiome, and Cancer: Understanding Disease Progression and What We Can Do to Prevent It

Armstrong

Bording-Jorgensen

Dijk

et al. 2018

Cancers

View full text Add to dashboard Cite

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“…Neural tube defects sering dikaitkan dengan defisiensi asam folat pada ibu hamil. Adapun defisiensi folat juga berhubungan dengan berat badan lahir rendah, persalinan prematur, keguguran, kelainan bawaan pada bayi dan preeklamsia (Valentin et al, 2018).…”

Section: Pendahuluanunclassified

“…Penyebab defisiensi ini bermacammacam antara lain gizi buruk, kurang konsumsi buah-buahan atau sayuran segar, asupan energi yang tidak memadai, sering membatasi diet tanpa kendali medis. Pil kontrasepsi oral, konsumsi alkohol dan tembakau berlebihan, serta beberapa perawatan medis (antikonvulsan) juga meningkatkan risiko defisiensi asam folat (Valentin et al, 2018).…”

Section: Pendahuluanunclassified

“…Asam valproat, obat antiepilepsi yang digunakan juga untuk pengobatan bipolar dan gangguan kepribadian juga meningkatkan 10 hingga 20 kali lipat risiko NTD (Wlodarczyk, Palacios, George, & Finnell, 2012 (Copp et al, 2013). Tes PRIUM, yang mencoba untuk memperbaiki mielomeningokel in utero sedang dilakukan di Prancis (Valentin et al, 2018).…”

Section: Pendahuluanunclassified

“…Vitamin B9 sangat penting untuk perkembangan embriologik. Efek perlindungannya juga terlibat dalam pencegahan penyakit Alzheimer, penyakit kardiovaskular, dan bahkan pada beberapa jenis kanker (Valentin et al, 2018 (Kondo et al, 2017).…”

Section: Suplementasi Asam Folatunclassified

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Folic Acid Supplementation can Reduce the Risk of Neural Tube Defects in Fetus

Rofi'atunnisa'

2019

jppp

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Cacat tabung saraf termasuk kelainan pada janin yang paling sering terjadi setelah kelainan jantung dan kelainan pada sistem genitourinari. Penyebab terjadinya cacat tabung saraf umumnya multifaktorial salah satu penyebab cacat tabung saraf adalah defisiensi asam folat. Asam folat sangat penting untuk perkembangan embriologik selama kehamilan. Kebanyakan kasus defisiensi asam folat sering tidak terdiagnosis. Banyak ibu hamil yang tidak menyadari dirinya mengalami defisiensi asam folat. Tujuan dari pemaparan tulisan ini adalah untuk mengetahui pengaruh suplementasi asam folat terhadap penurunan resiko cacat tabung saraf pada janin. Penelitian ini menggunakan metode literature review dengan penelusuran yang bersumber dari database NCBI, peneliti hanya menjaring artikel yang dipublikasi dalam kurun waktu antara tahun 2010-2020. Dari seluruh artikel yang didapat, sebanyak 25 artikel dipilih yang selanjutnya dianalisis menggunakan metode systematic literature review yaitu dengan membandingkan dari segi judul, pendekatan, tujuan, hasil dan pembahasan, kemudian ditelaah dan disusun secara sistematis. Dari beberapa sumber yang telah didapatkan menyebutkan bahwa suplementasi asam folat dapat menurunkan risiko cacat tabung saraf pada janin. Kata kunci: cacat tabung saraf; kehamilan; suplementasi asam folat FOLIC ACID SUPPLEMENTATION CAN REDUCE THE RISK OF NEURAL TUBE DEFECTS IN FETUS

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An innovative bioanalytical research project course to train undergraduate students on liquid chromatography–mass spectrometry

Alneyadi

Shah

Ashraf

2019

Biochem Molecular Bio Educ

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Active‐learning strategies such as undergraduate research courses and course‐based undergraduate research experiences (CUREs), which engage students in the practical experiments, have been reported as efficient ways for effective teaching and training of graduating students. Recently, many practical examples have been published in various fields to develop critical skills needed by undergraduate students for graduate school or the workforce; however, very few examples have been published for bioanalytical topics, specifically, Liquid Chromatography–Mass Spectrometry (LC–MS–MS). Herein, we describe an innovative undergraduate research course that was used to train well‐prepared graduating seniors on LC–MS–MS and in developing a sensitive method for detecting vitamin B9 (folic acid) levels in different milk samples. During this semester‐long exercise, the students were exposed to literature review, basic UV–Vis spectroscopy, and HPLC and LC–MS–MS techniques. Additionally, as part of this laboratory‐based research course, they researched published approaches on analyzing folic acid in food samples and devised a method to extract and quantify folic acid levels in different brands of milk using LC–MS–MS instruments. Feedback from students and faculty members was very positive as the students felt that this opportunity helped them to become more comfortable using HPLC and LC–MS–MS instruments and felt empowered to answer real‐life analytical problems. This laboratory‐based undergraduate research course can also be modified and used as an advanced bioanalytical laboratory exercise in biochemistry or analytical chemistry courses. © 2019 International Union of Biochemistry and Molecular Biology, 47(3):228–238, 2019.

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Acid folic and pregnancy: A mandatory supplementation

Cited by 33 publications

References 11 publications

The Complex Interplay between Chronic Inflammation, the Microbiome, and Cancer: Understanding Disease Progression and What We Can Do to Prevent It

The Complex Interplay between Chronic Inflammation, the Microbiome, and Cancer: Understanding Disease Progression and What We Can Do to Prevent It

Folic Acid Supplementation can Reduce the Risk of Neural Tube Defects in Fetus

An innovative bioanalytical research project course to train undergraduate students on liquid chromatography–mass spectrometry

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