Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness

Katibi, Oludolapo Sherifat; Olaosebikan, Rasaq; Abdulkadir, Mohammed Baba; Ogunkunle, Taofik Oluwaseun; Ibraheem, Rasheedat Mobolaji; Murtala, Rukayat

doi:10.4269/ajtmh.15-0348

Cited by 19 publications

(21 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In severe cases, it can cause seizures, coma and death, usually within 48 hours of ingestion. There can be associated hypoglycemia, and aciduria [1,3,9,17]. It may also be associated with toxic liver injury with histology mimicking Acetaminophen overdose [1,18,19].…”

Section: Resultsmentioning

confidence: 99%

“…Ackee fruit is known scientifically as Blighia sapida belonging to the Sapindaceae family [3]. It consists of the pod, the seeds, and the fleshy covering or aril.…”

Section: Discussionmentioning

confidence: 99%

“…This usually manifests as an acute gastrointestinal illness but can also be characterized by hypoglycemia and CNS depression [3]. The number of reported cases of Jamaican vomiting sickness has decreased over the years with better education and awareness among the local population about potential dangerous effects of ingestion of the unripe fruit.…”

mentioning

confidence: 99%

See 2 more Smart Citations

New Development of Hypoglycemia in a Previously Poorly-Controlled Type 2 Diabetic: Ackee Fruit-Induced Hypoglycemia

Latif¹,

Luthra²

2017

Int J Diabetes Clin Res

View full text Add to dashboard Cite

Objective: To report a case of hypoglycemia due to Ackee fruit consumption.Methods: This is a case report and brief review of literature. Results:We report a patient with new onset hypoglycemia due to the consumption of the Ackee fruit. Patient is a 95-year-old Jamaican male with history of uncontrolled, insulin requiring Type 2 diabetes mellitus. He presented with new onset of hypoglycemia and improvement in hemoglobin A1C without any changes in diabetes regimen, other medications or co-morbidities. On investigative questioning, he reported that he had recently received a jar of preserved Ackee fruit, and was consuming small portions of it daily. This coincided with the development of hypoglycemia. Conclusion:Despite being uncommonly used in the United States, Ackee fruit consumption is a known cause of hypoglycemia. Ackee fruit contains two toxins, hypoglycin A and hypoglycin B that work through the same mechanism to deplete hepatic glycogen stores and cause refractory hypoglycemia. The most severe form of Ackee-fruit toxicity is known as "Jamaican Vomiting Sickness". The disorder is characterized by symptoms of severe hypoglycemia and seizures, ultimately leading to coma and death. Although rare in the United States, it is important to understand and recognize the symptoms of Ackee fruit induced toxicity to avoid late detection and severe complications.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Ackee fruit is known scientifically as Blighia sapida belonging to the Sapindaceae family [3]. It consists of the pod, the seeds, and the fleshy covering or aril.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

New Development of Hypoglycemia in a Previously Poorly-Controlled Type 2 Diabetic: Ackee Fruit-Induced Hypoglycemia

Latif¹,

Luthra²

2017

Int J Diabetes Clin Res

View full text Add to dashboard Cite

show abstract

“…Several research results on the beneficial uses of B. sapida arils show that it is an essential element that should not to be neglected in diet in many regions due to it lipids (45%), proteins (11%), ash (4%) and vitamin C (65 mg/kg) content (Morton, 1987;Akintayo et al, 2002;Ouattara et al, 2010). Nevertheless, some molecules such as hypoglycine A, saponin, saccharides and fructoligosaccharides (Jimoh et al, 2007;Benkeblia and Lopez, 2015) have negative effects on the organism function (Moyal, 1985(Moyal, , 1986Chase et al, 1990;CDC, 1992;Bouree et al, 2002;OPS, 2002;Katibi et al, 2015). These negative effects can end up with death caused by hypoglycemia or hemolytic syndrome (Moyal, 1985(Moyal, , 1986CDC, 1992;Bouree et al, 2002;OPS, 2002;Katibi et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Nevertheless, some molecules such as hypoglycine A, saponin, saccharides and fructoligosaccharides (Jimoh et al, 2007;Benkeblia and Lopez, 2015) have negative effects on the organism function (Moyal, 1985(Moyal, , 1986Chase et al, 1990;CDC, 1992;Bouree et al, 2002;OPS, 2002;Katibi et al, 2015). These negative effects can end up with death caused by hypoglycemia or hemolytic syndrome (Moyal, 1985(Moyal, , 1986CDC, 1992;Bouree et al, 2002;OPS, 2002;Katibi et al, 2015). Despite everything, potentialities of B. sapida arils have been exploited in Côte d'Ivoire and in Jamaica when there were natural disasters in these countries.…”

Section: Introductionmentioning

confidence: 99%

Impact of Blighia sapida (k. Koenig) aril powder level in diet on the growth and the well-being of albino Wistar rats

HowÃ©lÃ©¹,

Meïté²,

Paul³

et al. 2016

Afr. J. Food Sci.

View full text Add to dashboard Cite

The aim of the present investigation was to evaluate the impact of Blighia sapida aril level in diet on the growth of albino Wistar rats and their welfare. A quantity of B. sapida arils was cooked and lyophilized. Thirty six young albinos Wistar rats teams up in six with six homogeneous groups were used for a four weeks research. Young rats group were fed ad libitum with six different diets which can be distinguished by the level of B. sapida arils powder. There were control diet (0% B. sapida arils powder), diet Bs 1 (6.25% B. sapida arils powder), diet Bs 2 (12.5% B. sapida arils powder), diet Bs 3 (25% B. sapida arils powder), diet Bs 4 (50% B. sapida arils powder) and diet Bs 5 (75% B. sapida arils powder). Body weight was measured weekly and the animals were observed for signs of abnormalities throughout the study. At the end of the experimentation, blood sample was collected and analyzed. Results show that the growth of rats fed with diets Bs 1 , Bs 2 and Bs 3 were normal as compared to the growth of rats fed with the control diet. On the other hand, growth retardation was noticed on rats fed with diets Bs 4 and Bs 5. However, rats coat fed with diets Bs 4 and Bs 5 were also normal. Again, for rats fed with diets Bs 4 and Bs 5 , a level (p<0.05) of total cholesterol and LDL-cholesterol was noticed as compared to values obtained in rats of the other groups.In the case of natural disaster, the consumption of B. sapida aril could be used as nutritional base at a degree neighboring 50% of the nutritional need of the organism. Outside this value, growth retardation and a level of total cholesterol and LDL-cholesterol can be noticed.

show abstract

Masqueraders of Anaphylaxis

Upton

2020

Anaphylaxis

View full text Add to dashboard Cite

Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness

Cited by 19 publications

References 9 publications

New Development of Hypoglycemia in a Previously Poorly-Controlled Type 2 Diabetic: Ackee Fruit-Induced Hypoglycemia

New Development of Hypoglycemia in a Previously Poorly-Controlled Type 2 Diabetic: Ackee Fruit-Induced Hypoglycemia

Impact of Blighia sapida (k. Koenig) aril powder level in diet on the growth and the well-being of albino Wistar rats

Masqueraders of Anaphylaxis

Contact Info

Product

Resources

About