Acne-associated spondylarthropathy: radiographic features.

Ellis, Burton I.; Shier, Christopher K.; Leisen, J J; Kastan, David J.; McGoey, Joseph

doi:10.1148/radiology.162.2.2948214

Cited by 56 publications

(33 citation statements)

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“…In contrast to other types of seronegative forms of SpA, an association with the histocompatibility antigen HLA-B27 in HS patients does not seem to exist [22,27,32] . Importantly, we did not observe any association between body height, body weight, BMI, smoking habits and the appearance of back pain or SpA, suggesting no major influence of lifestyle on the occurrence of back pain and SpA.…”

Section: Discussionmentioning

confidence: 61%

“…This initial description from 1982 was followed by a number of case reports and few small case series [21,[23][24][25][26] . The observed radiographic alterations in HS patients were described as indistinguishable from those of other seronegative forms of SpA [27] . Our precise MRI analyses [28,29] disclosed a surprisingly high number of typical changes suggesting SpA-related sacroiliitis in 56.5% of the patients.…”

Section: Discussionmentioning

confidence: 77%

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High Prevalence of Back Pain and Axial Spondyloarthropathy in Patients with Hidradenitis Suppurativa

Schneider‐Burrus

Witte-Haendel²,

Christou³

et al. 2016

Dermatology

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Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease, causing fistulating sinuses in the intertriginous skin of axillary, genitofemoral and perianal sites. Objective: As other chronic inflammatory diseases, e.g. psoriasis, are frequently associated with spondyloarthropathies (SpA), the goal of this study was to quantify the prevalence of back pain and SpA in HS patients. Methods: A prospective questionnaire survey in 100 HS patients and a retrospective evaluation of pelvic magnetic resonance imaging (MRI) scans in 46 HS patients were conducted. Results: 71% of HS patients were suffering from back pain. There was no difference between age at onset of HS, disease duration, body mass index (BMI), or disease severity between HS patients with and without back pain. Evaluating pelvic MRI scans, 32.6% of HS patients showed signs of chronic SpA and 39.1% signs of active SpA. Again, no significant differences between patients with/without SpA were found regarding age at time of MRI, age at onset of HS, disease duration, smoking habits, and BMI. Furthermore, there was no correlation between these parameters and the degree of SpA. Limitations: Only patients with moderate/severe HS (Hurley stage II and III) in genitofemoral/perianal sites were analysed via MRI scans. Conclusion: Back pain and SpA are very common among patients with moderate/severe HS. Neither medical history nor clinical parameters provide hints for the presence of SpA.

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Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 77%

High Prevalence of Back Pain and Axial Spondyloarthropathy in Patients with Hidradenitis Suppurativa

Schneider‐Burrus

Witte-Haendel²,

Christou³

et al. 2016

Dermatology

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“…A (24) 3 (10) 3 (10) 2 (7) Percentages are rounded off to nearest number * References 3,4,5,6,7,8,9,10. pyoderma gangrenosum, oral ulcers, urethritis, erythema nodusum or inflammatory bowel disease. Laboratory data Four of the nine patients had a normocytic, normochromic anaemia, leucocytosis with a normal differential and thrombocytosis.…”

Section: Resultsmentioning

confidence: 99%

“…The history, laboratory data and radiographs were reviewed and compared with 20 other cases previously reported.2-' Four additional cases were excluded because data presented was inadequate." Three cases with acne and well defined rheumatological syndromes, such as, Reiter's, (2) Crohn's disease (5) and human immunodeficiency virus infection (5) were also excluded.…”

Section: Methodsmentioning

confidence: 99%

Arthritis associated with hidradenitis suppurativa.

Bhalla

Sequeira

1994

Annals of the Rheumatic Diseases

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Objective-To review the presentation and clinical findings ofarthritis associated with hidradenitis suppurativa. Method-Medical records from the rheumatology clinics of two major teaching hospitals were reviewed for arthritis and hidradenitis suppurativa. The nine patient records fulfilling these criteria were reviewed and compared with 20 previous reports. Results and conclusion-The arthritis associated with hidradenitis suppurativa is rare and most commonly affects the peripheral joints. The axial skeleton is less frequently involved and is often asymptomatic.(Ann Rheum Dis 1994; 53: 64-66) Hydradenitis suppurativa is a suppurative condition of the apocrine sweat glands associated with induration, scarring, destruction of skin appendages and sinus formation.' Hydradenitis with acne conglobata and perifollicular capitis constitutes the follicular occlusion triad.'We describe nine patients with a seronegative arthropathy and associated skin manifestations of hidradenitis suppurative. This is the largest series of patients with these associated condition. Previous reports of five such patients have been isolated case reports.

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“…Axial skeletal involvement includes asymmetric paravertebral ossification of upper vertebrae and uni-or bilateral sacroiliac fusion. Peripherally, asymmetric erosive lesions and subluxation of any joints of the hands and feet may occur, including the distal interphalangeal joints, as well as the limbs (Ellis, 1987). In consequence, some suggest this form of arthropathy in African cases to be indistinguishable from certain cases of psoriatic arthritis or Reiter's disease.…”

Section: Acne-associated Spondylarthropathymentioning

confidence: 99%

Psoriatic arthritis in a fifth-century Judean Desert monastery

Zias

Mitchell

1996

Am. J. Phys. Anthropol.

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Psoriatic arthritis is a greatly underreported seronegative erosive arthropathy, due to the ambiguous lesions it leaves on bone in all but the most severe cases. For a confident diagnosis of psoriatic arthritis to be made, sacroiliac and intervertebral joint fusion must be present together with erosive lesions of the peripheral skeleton including most especially the terminal interphalangeal joints. In modern times it is only a small percentage of cases who experience such debilitating disease, which may explain who so few cases of psoriatic arthritis can confidently be identified from past populations. This report describes this pathological condition as observed in the comingled skeletal remains of nine males and one female from the tomb of Paulus in the Byzantine Monastery of Martyrius, in the Judean Desert. Visual study was complemented using radiographic techniques along with scanning electron microscopy. Two adult males show characteristic lesions of psoriatic arthritis, demonstrating the form known as arthritis mutilans. A third individual shows less widespread erosive lesions which may signify a pauciarticular example of psoriatic arthritis, as is true of most cases in modern times, or the remains may represent Reiter's disease. During the Byzantine period the earlier practise of expelling those with disfiguring diseases (biblical leprosy) evolved into a philanthropic, caring philosophy where the sick were housed and fed out of charity, often within monasteries. The presence of these cases of psoriatic arthritis within such a Judean Desert monastery confirms earlier suggestions that psoriasis was one of the diseases included by those in the ancient eastern Mediterranean under the umbrella term of biblical leprosy.

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Acne-associated spondylarthropathy: radiographic features.

Cited by 56 publications

References 0 publications

High Prevalence of Back Pain and Axial Spondyloarthropathy in Patients with Hidradenitis Suppurativa

High Prevalence of Back Pain and Axial Spondyloarthropathy in Patients with Hidradenitis Suppurativa

Arthritis associated with hidradenitis suppurativa.

Psoriatic arthritis in a fifth-century Judean Desert monastery

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