Effusion cooled liners, commonly used in gas turbine combustion chambers to reduce wall temperature, may also help reducing the propagation of pressure fluctuations due to thermoacoustic instabilities.Large Eddy Simulations were conducted to accurately model the flow field and the acoustic response of effusion plates subject to a mean bias flow under external sinusoidal forcing. Even though existing lower order computational models showed good predicting capabilities, it is interesting to verify directly the influence of those parameters such as the staggered arrangement, the hole inclination, the presence of a grazing flow and the level of bias flow, which are not fully included in those models.A first bi-periodic single hole configuration with normal acoustic forcing was selected to investigate the acousting behavior with varying inclination angle, bias and grazing flow. 90 • and 30 • perforations were simulated for bias flow Mach number in the range 0.05-0.1 and grazing flow between 0 and 0.08. Those conditions were chosen to expand the knowledge of acoustic properties towards actual liners working conditions. A second more computationally expensive set-up, including 4 inclined holes at 30 • , focused on the damping of parallel to the plate waves.Details of the computational methods implemented in the general purpose open-source unstructured CFD code OpenFOAM R exploited to conduct this analysis are reported together with an analysis of the results obtained from the acoustic computations both regarding the flow field generated and the absorption and energy dissipation coefficient.