Acoustic standing-wave enhancement of a fiber-optic Salmonella biosensor

Zhou, Chonghua; Pivarnik, Philip E.; Rand, Arthur G.; Letcher, S. V.

doi:10.1016/s0956-5663(97)00141-3

Cited by 25 publications

(8 citation statements)

References 10 publications

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“…• Military defense: hazards biomolecules, such as salmonella, anthrax, the H1N1 influenza virus, in the military defense point of view can represent a threat, since they can be considered powerful weapons in terrorists hands. The Salmonella bacteria fiber optic biosensor, developed by Zhou et al [69] in the late nineties, for example, is able to detect this pathogen in food and water, with a sensitivity as low as 10 4 cell colony forming unit/ml.…”

Section: Applications Of Biosensorsmentioning

confidence: 99%

New Insights on Optical Biosensors: Techniques, Construction and Application

Martins¹,

Ribeiro²,

Camargo³

et al. 2013

State of the Art in Biosensors - General Aspects

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Section: Applications Of Biosensorsmentioning

confidence: 99%

New Insights on Optical Biosensors: Techniques, Construction and Application

Martins¹,

Ribeiro²,

Camargo³

et al. 2013

State of the Art in Biosensors - General Aspects

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“…During the process, due to conflicting compression of erythrocytes and lipids, erythrocytes were gathered towards the pressure nodes, while lipids were aggregated towards the anti-pressure nodes. Yasuda et al (1997) attempted to concentrate erythrocytes inside blood at the pressure nodes in a 500 kHz ultrasonic standing wave, while Zhou et al (1998) were able to improve the detection performance of sensors by concentrating Salmonella in the suspension towards the pressure nodes in the same 500 kHz ultrasonic standing wave. Pui et al (1995) has developed a cell harvesting system by using an ultrasonic standing wave to align and aggregate cells, and then making them precipitate by gravity.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Particle Separation in Suspension using an Ultrasonic Standing Wave

Shin

Danao

2012

Journal of Biosystems Engineering

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Purpose: Particle separation in solution is one of important process in a unit operation as well as in an extract preparation for biosensors. Contrary to centrifuge-type of mesh-type filter, using an ultrasonic standing wave make the filtering process continuous and free from maintenance. It is needed to investigate the characteristics of particle movement in the ultrasonic standing wave field. Methods: Through the computer simulation the effects of major design and driving parameters on the alignment characteristics of particles were investigated, and a cylindrical chamber with up-stream flow type was devised using two circular-shape PZTs on both sides of the chamber, one for transmitting ultrasonic wave and the other for just reflecting it. Then, the system performance was experimentally investigated as well. Results: The speed of a particle to reach pressure-node plane increased as the acoustic pressure and size of particle increased. The maximum allowable up-stream flow rate could be calculated as well. As expected, exact numbers of pressure-node planes were well formed at specific locations according to the wavelength of ultrasonic wave. As the driving frequency of PZT got close to its resonance frequency, the bands of particles were observed clearer, which meant the particles were trapped into narrower space. Higher excitation voltages to the PZT produced a greater acoustic force with which to trap particles in the pressure-node planes, so that the particles gathered could move upwards without disturbing their alignments even at a higher inlet flow rate. Conclusions: This research showed the feasibility of particle separation in solution in the continuous way by an ultrasonic standing wave. Further study is needed to develop a device to collect or harvest those separated particles.

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“…The acoustic wave devices have been extensively investigated in the field of biodetection in the past years, since the directness, immediateness, high sensitivity and low cost [1][2][3][4][5][6][7]. The principle of those AW biosensor platforms are based on the resonance frequency shift due to the mass load on the surface.…”

Section: Introductionmentioning

confidence: 99%

Piezoelectric Membrane Based Biosensor Platform

Lü

et al. 2010

Ferroelectrics

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The piezoelectric membrane, working as flexural acoustic wave devices, is introduced as high performance biosensor platform. Membranes made of polyvinylidene fluoride (PVDF) thin film were fabricated and the influences of size and stress on the resonance behaviors have been investigated. It is experimentally found that membrane could exhibits a nearly same Q factor both in air and in water. Additionally, the microelectronic process combined with megnetron sputtering deposition for fabricating ZnO micro membrane biosensor platform on silicon wafer is established in this paper.

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Acoustic standing-wave enhancement of a fiber-optic Salmonella biosensor

Cited by 25 publications

References 10 publications

New Insights on Optical Biosensors: Techniques, Construction and Application

New Insights on Optical Biosensors: Techniques, Construction and Application

Characteristics of Particle Separation in Suspension using an Ultrasonic Standing Wave

Piezoelectric Membrane Based Biosensor Platform

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