Acquired supravalvular pulmonary stenosis due to extrinsic compression by a metastatic thymic carcinoid tumor

Lynch, Mary; Blevins, Lewis S.; Martin, Randolph P.

doi:10.1007/bf01798117

Cited by 10 publications

(7 citation statements)

References 4 publications

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“…Recognition even by experienced teams relies on advanced imaging including magnetic resonance and PET. Secondly, extrinsic compression by lymph nodes or mediastinal tumours, for example a metastatic thymic carcinoid tumour, can cause extrinsic compression mimicking stenosis of the pulmonary valve and apparent PH [67].…”

Section: Other Causes Of Tumoral Phmentioning

confidence: 99%

Tumoral pulmonary hypertension

et al. 2019

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Tumoral pulmonary hypertension (PH) comprises a variety of subtypes in patients with a current or previous malignancy. Tumoral PH principally includes the tumour-related pulmonary microvascular conditions pulmonary tumour microembolism and pulmonary tumour thrombotic microangiopathy. These inter-related conditions are frequently found inpost mortemspecimens but are notoriously difficult to diagnoseante mortem. The outlook for patients remains extremely poor although there is some emerging evidence that pulmonary vasodilators and anti-inflammatory approaches may improve survival. Tumoral PH also includes pulmonary macroembolism and tumours that involve the proximal pulmonary vasculature, such as angiosarcoma; both may mimic pulmonary embolism and chronic thromboembolic PH. Finally, tumoral PH may develop in response to treatments of an underlying malignancy. There is increasing interest in pulmonary arterial hypertension induced by tyrosine kinase inhibitors, such as dasatanib. In addition, radiotherapy and chemotherapeutic agents such as mitomycin-C can cause pulmonary veno-occlusive disease. Tumoral PH should be considered in any patient presenting with unexplained PH, especially if it is poorly responsive to standard approaches or there is a history of malignancy. This article will describe subtypes of tumoral PH, their pathophysiology, investigation and management options in turn.

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Section: Other Causes Of Tumoral Phmentioning

confidence: 99%

Tumoral pulmonary hypertension

et al. 2019

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“…Isolated supravalvular pulmonary stenosis is less common than other types of pulmonary stenosis and is commonly associated with the congenital rubella syndrome . More commonly, isolated obstruction of the pulmonary artery is due to extrinsic compression or to intraluminal invasion by thoracic neoplasm …”

Section: Discussionmentioning

confidence: 99%

“…2 More commonly, isolated obstruction of the pulmonary artery is due to extrinsic compression or to intraluminal invasion by thoracic neoplasm. [3][4][5] Some patients may have residual or secondary supravalvular pulmonary stenosis or peripheral pulmonary stenosis after surgical procedures such as mechanical pulmonary valve replacement, which necessitates an additional interventional therapy, 6 or after an arterial switch operation for transposition of great arteries with intact ventricular septum, which is the most common cause of reintervention. 7 In this case report, none of the above mentioned causes is involved in the genesis of pulmonary stenosis, which is to be considered congenital.…”

Section: Discussionmentioning

confidence: 99%

Isolated Supravalvular Pulmonary Stenosis: A Rare Echocardiographic Finding

et al. 2014

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Isolated supravalvular pulmonary stenosis is a rare finding, usually evidenced in the pediatric age. Here, we report a case of a 76-year-old patient with isolated, severely obstructive, pulmonary supravalvular stenosis. The peculiarity of the present case is the paucity of symptoms and lack of changes in right heart sections, despite of the importance of stenosis. The report confirms the utility of transthoracic two- and three-dimensional echocardiography and transesophageal echocardiography in the detection and quantification of this rare anomaly.

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“…Stenosis of the main pulmonary artery is commonly associated with the congenital rubella syndrome; however, it usually occurs with other congenital defects, including sensorineural deafness, cataracts, patent ductus arteriosus, septal defects, and peripheral branch pulmonary artery stenosis 2 . More commonly, isolated obstruction of the pulmonary artery is due to extrinsic compression or to intraluminal invasion by thoracic neoplasm, such as carcinoid tumors 3–5 …”

mentioning

confidence: 99%

“…2 More commonly, isolated obstruction of the pulmonary artery is due to extrinsic compression or to intraluminal invasion by thoracic neoplasm, such as carcinoid tumors. [3][4][5]…”

mentioning

confidence: 99%

Isolated Supravalvular Pulmonary Artery Ridge in a 70‐Year‐Old Man

Gilman¹,

Hansen²,

Glockner³

et al. 2006

Echocardiography

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Transthoracic echocardiography allows noninvasive assessment of the structure and function of the great vessels of the heart. We report a case of a 70-year-old man who had an isolated, mildly obstructive, supravalvular pulmonary artery ridge that was detected incidentally with transthoracic echocardiography. This report confirms the utility of transthoracic echocardiography in the detection of this condition and discusses quantification of this rare anomaly.

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Acquired supravalvular pulmonary stenosis due to extrinsic compression by a metastatic thymic carcinoid tumor

Cited by 10 publications

References 4 publications

Tumoral pulmonary hypertension

Tumoral pulmonary hypertension

Isolated Supravalvular Pulmonary Stenosis: A Rare Echocardiographic Finding

Isolated Supravalvular Pulmonary Artery Ridge in a 70‐Year‐Old Man

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